Asparkam is a source of potassium and magnesium, because it contains these elements in a form that allows them to pass inside the cells and fully digested. The drug restores the electrolyte balance, if it was disturbed, and is a source of potassium and magnesium for the body.
Potassium has anti-arrhythmic effect, thereby maintaining normal and regular heart function without arrhythmias. Magnesium is involved in ensuring the flow of more than 300 different biological reactions in the human body, necessary for the maintenance of vital activity and normal metabolism. In addition, magnesium improves the penetration of potassium ions into cells.
Asparkam is used for heart failure, myocardial infarction, arrhythmias, to eliminate the effects of intoxication caused by the use of cardiac glycosides (Strofantin, Digoxin, Korglikon, Digitoksin, Celonid, etc.), as well as to restore the balance of ions with potassium deficiency (hypokalemia) and magnesium ( hypomagnesemia) in the body.
Asparkam – composition, release forms, dosages, types
Today under one common name "Aspark" implies several types of the drug, produced by different pharmaceutical companies under different names. As a rule, these names always contain the word "Aspark", to which are added a few letters related to the multiple name of the enterprise manufacturing this particular preparation, for example, "Asparkam-Ferein", "Asparkam-Farmak" and
Different names for the same Asparkam are necessary in order to register the products of any pharmaceutical company on the market. The fact is that during the period of the USSR, all pharmaceutical plants produced medicines using the same technology and under the same name, for example, acetylsalicylic acid was called that way, although it could be produced in Nizhny Novgorod, Perm, Novokuznetsk and
In addition, some varieties of Asparkam can be produced only in one dosage form, because the company has developed the technology of production of this particular form, and not any other. For example, "Asparkam-Farmak" and "Asparkam-Ferein" are made only in the form of solution for injection, and tablets are not produced at these pharmaceutical companies, since the necessary technology is missing or it is not possible to master it.
So, at present, various pharmaceutical plants produce the following varieties of Asparkam:
These types of the same drug differ only in their names, so in the following text we will all designate them by one common name. "Aspark".
Asparkam species are available in the following dosage forms:
- Tablets for oral administration (Asparkam, Asparkam-ROS, Asparkam-UBF);
- Solution for intravenous injection in ampoules of 5 ml, 10 ml and 20 ml (Asparkam, Asparkam-L, Asparkam-Farmak, Asparkam-Ferein);
- Solution for intravenous infusions – "droppers" in bottles of 200 ml and 400 ml (Asparkam-L).
The composition of all forms of Asparkam includes two compounds – potassium asparaginate and magnesium asparaginate. These compounds are salts of potassium and magnesium, which penetrate the cells well due to aspartic acid. In the process of penetration into the cell ions of potassium and magnesium are released from asparaginate, and therefore they are the main active ingredients of the drug.
The various dosage forms of Asparkam contain the following amounts of potassium and magnesium in the form of asparaginate:
- Tablets – 175 mg of potassium asparaginate and 175 mg of magnesium asparaginate (175 + 175);
- Solution for injection – 40 mg of magnesium asparaginate (3.37 mg of pure magnesium) and 45.2 mg of potassium asparaginate (10.33 mg of pure potassium) in 1 ml;
- The solution for infusion – 7.9 g of magnesium asparaginate and 11.6 g of potassium asparaginate in 1 liter.
Asparkam tablets have a specific odor, and as auxiliary components contain corn starch, calcium stearate, talc and polysorbate-80. Solutions for injection and infusion as auxiliary components contain only sorbitol and sterile water.
Therapeutic Effects of Asparkam
Asparkam is a source of potassium and magnesium ions, respectively, its therapeutic effects are due to the action of precisely these chemical elements. First of all Asparkam eliminates an imbalance or deficiency of potassium and magnesium in the body, and also has the ability to regulate metabolic processes, since these ions are involved in many biochemical reactions in all organs and tissues.
Potassium is the main intracellular positive ion in all organs and tissues. Being in the cell in sufficient quantity, potassium stimulates the synthesis of ATP (adenosine triphosphate), glycogen, proteins and acetylcholine.
ATP is a universal energy molecule, which is necessary for the occurrence of any reactions and the implementation of cell functions. In its role, ATP can be compared with gasoline for a car engine. That is, without ATP, the cell simply cannot do anything, even provide its own nutrition and reproduction. Potassium, stimulating the synthesis of ATP, allows the cell to receive a large amount of energy, which is enough to perform specific functions (for example, muscle contractions, hydrochloric acid production and
Stimulation of glycogen synthesis allows the cell to create a strategic reserve of a substance that can be quickly converted into ATP during hunger. That is, under the influence of potassium, cells create stocks of peculiar "semi-finished products" during periods of life when energy is low.
Stimulation of protein synthesis allows the cell to replace in time "the old" molecules that already poorly cope with their functions, with new ones that have the ability to work quickly and easily. Such a phenomenon can be compared with the replacement of old and worn parts on a car or any other device. Naturally, after replacing old parts with new ones, the device will work better. The same is true in the cells of the body – replacing old proteins with new ones allows cellular elements to work better, more efficiently and longer.
Stimulation of acetylcholine synthesis allows the cell to accelerate the conduction of various signals along the nerve fibers, since it is this substance that is the mediator that performs the function of nerve activation.
Thus, potassium ions accelerate the work of the cell, increase its efficiency, and also allow you to quickly respond to commands from the nerve trunks and create reserves of energetic substances.
Magnesium is necessary for the operation of more than 300 enzymes that ensure the metabolism and the specific functions of each cell in the body. Magnesium also participates in the cascade of reactions for the synthesis of ATP and regulates the balance of potassium. Thus, magnesium enhances the effects of potassium and makes the work of the cell more efficient, faster and more versatile.
In addition, together the ions of potassium and magnesium support the necessary polarization of cell membranes, which is necessary for the effective separation of the external environment and the internal cellular cytoplasm. Due to this distinction of environments, unnecessary and harmful substances do not enter the cells, and metabolic products are removed from it outside.
Asparaginate is a carrier of potassium and magnesium ions through the membrane inside the cells. After penetration into the cell, potassium and magnesium are released from the bond with asparaginate, and it is involved in the process of metabolism. Aspartate improves the synthesis of replaceable amino acids, nucleotides for DNA and lipids. In addition, asparaginate optimizes energy metabolism in heart muscle experiencing oxygen deprivation, for example, in ischemic disease, atherosclerosis, and
It should be remembered that Asparkam has all of the above effects in the cells of all organs and tissues, but they are most noticeable in relation to the heart. Therefore, Asparkam is traditionally used in the complex treatment of heart diseases, especially arrhythmias, since it has the following effects in relation to this most important organ:
- Prevents and eliminates hypokalemia (deficiency of potassium in the blood);
- Improves metabolism in the heart muscle;
- Eliminates arrhythmias that occur after myocardial infarction or on the background of heart failure;
- Improves the tolerance of cardiac glycosides (Strofantina, Digoxin, Korglikon, Digitoxin, Celanid, etc.);
- Increases the endurance of the heart and allows you to perform more physical work and endure much stronger emotions.
Asparkam – indications for use (what is used)
Asparks are indicated for use in the treatment of the following diseases and conditions:
- Heart failure;
- Coronary heart disease (CHD);
- Postinfarction period;
- Heart rhythm disorders (paroxysmal supraventricular tachycardia, atrial and ventricular premature beats) caused by various causes, including myocardial infarction and overdose of cardiac glycosides;
- Digitalis intoxication (poor tolerance or poisoning by cardiac glycosides).
In addition, Asparkam as an independent drug is indicated for use in hypokalemia (potassium content in the blood is below normal) and hypomagnesemia (magnesium content in the blood is below normal) of any origin. When hypomagnesemia and hypokalemia Asparkam used to normalize the concentration of magnesium ions and potassium in the blood. You should know that Asparks can be used to eliminate the deficiency of potassium and magnesium of any origin, for example, after repeated vomiting, diarrhea, taking non-calcium-saving diuretic (for example, Furosemide), laxative drugs and glucocorticosteroids.
In addition, separately it is necessary to highlight the recommendations (which can be considered as indications for use) on the use of Asparkam in sports:
- Long and intensive physical activity;
- Heart rhythm disorder.
Asparkam – instructions for use
Tablets should be swallowed whole, not chewing, not chewing, not breaking and grinding in other ways, but with a small amount of water (half a cup is enough).
For therapeutic purposes, it is recommended to take 2 tablets 3 times a day after meals. The duration of the course of therapy is 3-4 weeks. If necessary, such courses of therapy can be repeated every 1 to 3 months.
Acceptance of Asparkam for the prevention of potassium and magnesium deficiency, as well as in sports, 1 tablet 3 times a day after meals. The duration of prophylactic administration is determined individually and can be long. When taking Asparkam for more than 4 weeks, it is recommended that you take a blood test to determine the concentration of potassium and magnesium every 7 to 14 days. If those are at the upper limit of the norm or slightly exceed it, then you should stop taking Asparkam for a while. In this situation, it will be possible to resume taking the drug only when the concentration of potassium and magnesium in the blood drops to normal values.
Neither with therapeutic nor prophylactic purposes one should take more than 6 tablets of Asparkam per day, since excessively high dosages of potassium and magnesium are not absorbed, but simply excreted in the urine. That is, 6 tablets taken during the day will be absorbed, and all others will simply be removed from the body. Attempts to take more than 6 tablets of Asparkam per day lead only to an increased load on the kidneys, which can adversely affect their functioning and, consequently, the well-being of the person.
Instructions for use of solutions for intravenous injection and for infusion
Solutions for infusions and for injections are administered intravenously exclusively for treatment and never for prophylaxis and in sport. In order to improve the endurance of the heart and the prevention of potassium and magnesium deficiency should take Asparkam only tablets.
Injection solutions are available in 5 ml, 10 ml and 20 ml ampoules under the names Asparkam, Asparkam-L, Asparkam-Pharmak, Asparkam-Ferein and have the same concentrations of potassium and magnesium. Infusion Solution is available in 200 ml and 400 ml bottles called Asparkam-L.
Injection solutions can be administered in streams (slowly jetting out directly from a syringe) or used to prepare an infusion solution ("droppers"). The solution for infusion is used only for drip, that is, for what is commonly called "drip".
Use only clear solutions for injections and infusions. If a cloudy solution is in the bottle or in the ampoule, it should be discarded. After opening the ampoule or bottle, you should immediately use the solution. If after mixing Asparkam in one syringe or bottle with other solutions for infusions, turbidity has occurred, then such mixtures cannot be injected, they must be discarded.
With the purpose of treatment in the complex treatment of various heart diseases, solutions for injections of Asparkam are administered daily to 10-20 ml 1 to 2 times a day for five days. Before administration, half the amount of saline or 5% dextrose solution is added to Asparkam, for example, 5 ml of saline or 5% dextrose solution is taken per 10 ml of Asparkam.
Infusion Solution is only used for "droppers", that is, administered intravenously. For therapeutic purposes, inject 300 ml of the prepared solution for infusion 1 to 2 times a day for a maximum of 5 days. The solution is injected at a rate of 20-30 drops per minute (1-1.5 ml per minute).
If there is no solution for infusions for some reason, but it is necessary to introduce Aspark to the person in the "droppers", it is possible to use ampoules with a solution for injection. In this case, the solution for infusion prepared from a solution for injection. To do this, for every 10 ml of solution for injection from ampoules add 100 ml of saline or 5% dextrose solution.
That is, if a person needs to inject 300 ml of the solution for infusions, then to obtain it, 30 ml of the solution for injection should be poured from the ampoules and 300 ml of physiological saline should be added to it. The solution for infusion thus obtained is also administered at a rate of 20 to 30 drops per minute.
Special instructions and precautionary measures
Overdose of Asparkam is possible only with intravenous administration of solutions and is manifested by the following symptoms:
- Bradycardia (slow heartbeat);
- Lowering blood pressure;
- Vascular collapse;
- Diastolic cardiac arrest;
- Bladder weakness;
- Heart block;
- Respiratory paralysis;
- Paralysis of the heart muscle with cardiac arrest.
For the treatment of Asparkam overdose, a solution of calcium chloride, which neutralizes excess potassium and magnesium ions, should be administered intravenously. To accelerate the excretion of ions can be using hemodialysis.
When taking pills Asparkam overdose has not been recorded even once.
Interaction with other drugs
The use of Asparkam inhibits intestinal peristalsis and provokes constipation, and also increases the risk of hyperkalemia (elevated levels of potassium in the blood) due to excessive accumulation of potassium ions in the blood in combination with the following drugs:
- Potassium-sparing diuretic drugs (for example, Veroshpiron, Spironolactone and
Asparkam reduces toxicity and improves the tolerance of cardiac glycosides by eliminating their side effects.
When using non-potassium-sparing diuretic drugs (Furosemide and others) and glucocorticosteroids (Dexamethasone, Prednisolone and
Asparkam enhances the effects of anti-depolarizing muscle relaxants (Pipecuronium, Pancuronium, Tubocurarine and
Asparks for children and baby
Asparks for children older than one year old and infants are prescribed only in cases when there is a deficiency of potassium in the blood (hypokalemia) according to the results of laboratory examinations. If according to the results of blood tests for ions, hypokalemia was detected, then regardless of the reasons that provoked this violation, the child is prescribed Asparkam tablets. Intravenous injections are extremely rare, only in the case of life threatening.
Hypokalemia in children is manifested by lethargy, drowsiness, apathy, muscle weakness, a drop in blood pressure, arrhythmia, and tachycardia (palpitations). If the baby is breast-fed, in addition to the indicated signs, hypokalemia can manifest itself as dry skin, increased flatulence, poor breast sucking and frequent regurgitation, up to vomiting.
Hypokalemia in a child of any age can develop for the following reasons:
- Repeated vomiting;
- Diarrhea for at least 24 hours;
- Severe liver or kidney disease;
- Diseases of the digestive tract;
- Use of glucocorticoids;
- The use of non-calcium diuretics;
- Intravenous administration of solutions of glucose, proteins and salts without potassium.
If a child has recently been exposed to the possible causative factors of the above listed hypokalemia factors, then blood should be donated to an ionogram, during which the doctor will determine the concentration of potassium. If that is low or close to the lower limit of the norm, then it is necessary to drink 1 to 2 weeks of Asparkam in individual dosages, which the doctor will prescribe. The drug is also prescribed to children for arresting arrhythmias caused by myocarditis, which usually develops as a complication of a viral or bacterial infection.
As a rule, in case of hypokalemia and arrhythmia, it is recommended that children be given asparkam for 1 to 2 weeks in the following dosages:
- Children younger than a year – 1/4 tablet 1 time per day;
- Children 1 – 3 years old – 1/2 tablet 1 time per day;
- Children 3 – 6 years old – 1/2 tablet 2 times a day;
- Children 7 – 10 years old – 1/2 tablet 3 times a day;
- Children 11 – 12 years old – 1 tablet 1 – 2 times a day;
- Children 13 – 16 years old – 1 tablet 2 times a day;
- Children 16 years old – 1 tablet 3 times a day.
These dosages are only indicative, so in each case it is better to consult a doctor who will determine the individual dosage, taking into account the characteristics of the child.
If a child takes diuretic drugs or glucocorticoids that promote the removal of potassium from the body, then doctors always additionally prescribe Asparks in prophylactic dosages to prevent the development of hypokalemia. The combination of Diacarb (diuretic drug) + Asparkam has become literally a classic prescribed for infants to reduce increased intracranial pressure. In this case, Asparkam and Diakarb are prescribed according to a certain scheme for a long term.
Use during pregnancy
Asparks during pregnancy can be taken simultaneously with non-calories-saving diuretics, as well as to improve the performance of the heart, if functional disturbances are detected on the ECG. In addition, Asparks can be used in short courses of 1-2 weeks for the prevention of hypokalemia, if a woman often has vomiting or diarrhea. In such cases, it is optimal to take 1 tablet of Asparkam 3 times a day for a week after 2 episodes of vomiting or diarrhea.
Application for various purposes not indicated in the instructions.
Asparkam and Riboxin + Asparkam in bodybuilding
In bodybuilding or sports, Asparks, alone or in combination with Riboxin, are taken to increase endurance, increase the time of effective workouts, as well as strength and cardiovascular exercise. In addition, Asparkam alone or in combination with Riboxin improves the condition and increases the productivity of the athlete’s heart, preparing and adapting it to high physical exertion, which, in turn, prevents sudden death from cardiac arrest, due to the fact that the body simply could not stand loads.
Asparkam is a source of potassium and magnesium, which reduce the heart rate and allow you to keep the pulse at loads within the required limits. That is, when applying Asparkam, even against the background of intense cardio or cardiovascular activity, the heart does not beat as often and strongly as without this drug. In addition, potassium and magnesium ions relax muscles well, eliminate excessive tension and relieve cramps. And since potassium and magnesium are intensively consumed under any power loads, then taking Asparkam makes it possible to replenish the level of ions in the blood and cells and to make workouts more efficiently.
Riboxin increases the volume of ejected blood and the force of contractions of the heart, which improves the blood supply to all organs and tissues in the body. In addition, Riboxin provides muscle recovery after an intense workout, relieves arrhythmias and helps to restore the structure of myocardial cells, which eliminates cardiomyopathy. We should also note the anabolic effect of the drug, which is useful for athletes and bodybuilders, which allows you to gain muscle mass faster.
Thus, both drugs are useful for athletes and bodybuilders, but most often they are used in combination, as Asparkam further enhances the effects of Riboxin. Asparks are recommended to take 1 tablet 3 times a day during the month, and Riboxin – 2 tablets 3 times a day also during the month. Courses of taking each drug separately or a mixture of Asparkam + Riboxin can be repeated every 3 months.
Asparkam for weight loss
Currently, the drug is widely used for weight loss, and some people combine it with diet and exercise, while others – with the reception of diuretics.
Acceptance of Asparkam in order to accelerate weight loss and achieve better results against the background of dieting, especially tight, and exercise is justified and useful. The fact is that with a diet, a person does not receive many of the substances he needs in sufficient quantities, including potassium and magnesium, which slows down the metabolism and lengthens the process of losing weight.
Asparkam allows you to fill the deficit of these elements in food and to ensure their intake in the body in sufficient quantities. And the potassium and magnesium contained in Asparkam enhance the effect of diet and exercise, because they speed up the metabolism, optimize muscle function and speed up the elimination of toxins resulting from the breakdown of fat cells, as a result, the person taking Asparks will lose weight faster and stronger than the one that does not use this drug.
Thus, the use of Asparkam for weight loss in combination with diet and exercise is rational and beneficial. In this case, the drug is recommended to take 1 tablet 3 times a day for 2 to 4 weeks.
The use of diuretic (furosemide, diacarb and other) drugs in combination with Asparkam to reduce weight is unjustified and dangerous. The fact is that under the influence of diuretic drugs, fluid is excreted from the body and dehydration occurs. Of course, due to this technique, the weight can be reduced by several kilograms, but due to dehydration, and not the breakdown of fat deposits, which in itself is dangerous. In this case, Asparkam only prevents the decrease in the concentration of potassium in the blood, since these ions are excreted by the kidneys under the action of diuretic drugs, but do not compensate for fluid loss and do not prevent the dangerous effects of dehydration.
How to take Asparks with diuretic drugs?
Diacarb or Furosemide and Asparkam
The combination of Diakarb + Asparkam and Furosemide + Asparkam is most often prescribed in the complex therapy of high blood pressure and edema, including the brain, with Diakarb or Furosemide being the main active drug in it. In addition, this combination of drugs is used in all cases when the use of diuretics is necessary.
The fact is that Diacarb and Furosemide are diuretic drugs, and therefore effectively remove fluid from the body, thereby reducing the volume of circulating blood, which naturally leads to a decrease in blood pressure. In addition, in response to a decrease in circulating blood volume, water from the tissues also begins to flow out and flow into the bloodstream, which, in turn, eliminates edema.
Asparkam in these combinations is necessary to replenish potassium in the blood, since Diacarb and Furosemide remove this trace element from the body. That is, Asparkam eliminates the side effect of Diacarb and Furosemide, which allows the use of a diuretic for a sufficiently long period of time required to achieve the desired clinical effect.
Diakarb and Asparkam baby
Diakarb and Asparkam baby is assigned to reduce intracranial pressure, eliminate cysts and dysfunction of the brain, as well as removing excess fluid from the ventricles of the brain. Under the action of Diacarb, water is eliminated from the body, as a result of which fluid from the tissues (in this case, the brain) enters the bloodstream, and brain swelling, hypertension and cysts are eliminated.
Diacarb must be used in combination with Asparkam, because it removes potassium from the body, and its deficiency can lead to serious complications, up to cardiac arrest. And in order to prevent potassium deficiency, along with Diacarb one should use Asparkam, which is a source of magnesium and potassium ions, which makes it possible to replenish their amount in the body.
Diakarb and Asparkam are prescribed to infants according to the following schemes: 1. Take 1/4 of Asparkam tablets and 1/4 of Diakarb tablets a day every three days during the month. That is, one day should give the child drugs, not to give three days and
Asparkam – reviews
Almost all reviews of Asparkam (over 97%) are positive, due to the pronounced and clearly visible clinical effects of the drug, which significantly improve the general condition of the person, normalize the heart, eliminate seizures and a number of other unpleasant symptoms caused by a lack of potassium and magnesium.
Most positive reviews about Asparkam are related to its use in serious diseases or functional disorders of the heart. People who took Asparks in the complex therapy of coronary insufficiency, coronary artery disease and other severe heart pathologies, note that they began to feel much better, their physical and emotional stress became more tolerable, their feelings of palpitations and fading disappeared. And people who took Asparks for functional disorders of the heart (for example, feeling pain, fading, frantic or irregular heartbeat, myocardiodystrophy, a sharp increase in heart rate during physical and emotional stress and
A slightly smaller part of reviews about Asparkam relates to its effectiveness in eliminating cramps in the limbs, which arise for various reasons. In the reviews, people note that literally after 2–3 weeks of use, the drug completely eliminated the convulsions and muscle tension that prevent normal work, sleep and good relaxation. Asparkam is effective for stopping seizures in pregnant women.
Women note that Asparkam reduces breast swelling and fluid retention before menstruation, and also reduces the severity of other PMS symptoms.
Reviews Diakarbe and Asparkame (infants)
Asparkam or Panangin?
Asparks and Panangin are synonymous drugs, because they contain exactly the same active substance in the same dosages. Therefore, in terms of clinical effects, both drugs are exactly the same. Some doctors and scientists believe that Panangin is more effective than Asparkam, however, specialized scientific studies have not revealed any advantage in one or another drug, therefore it is reasonable to consider them to be the same in terms of the severity of clinical effects. People who took Panangin and Asparkam also say in most cases that they did not feel any difference.
Thus, given the lack of objective differences between Asparkam and Panangin, you can choose any drug that, for any subjective reason, a person likes more. Since Panangin is an imported drug, and Asparkam is domestic, respectively, the first one is much more expensive than the second, therefore, if necessary, it is possible to save the choice on Asparkam. Read more about Panangina
Better than Aspark
There is no concept in medicine "best"because, due to the individual characteristics of the organism of each individual, it is impossible to make an ideal, absolutely suitable and equally well-tolerated drug. This means that among drugs with the same active substances, one person will have medicine X, and another one – Y. And the best medicine for a particular person can be calculated by testing. That is, a person will try to take several preparations-synonyms with the same active substances and choose for themselves what suits him best.
All this fully applies to Asparkam, which has several preparations-synonyms. If a person wants to pick something better than Aspark, he should try to take his preparations-synonyms and, thus, pick up a medicine that will be subjectively the best for him.
Asparkam – price
The author: Nasedkina