Forms of release
Unidox Solyutab Instructions
Unidox Solutab (hereinafter referred to as unidox) is an antibiotic from the tetracycline group. This is an original patented drug from the Dutch pharmaceutical concern Astellas Pharma Europe based on the well-known doxycycline since time immemorial. Interacting with the 30S ribosomal subunit of the bacterial cell, this antibiotic suppresses protein synthesis, which leads to inhibition of the growth and development of the microorganism (bacteriostatic action). Unidox is effective against a wide range of Gram-positive and Gram-negative “infectious provocateurs”, including Staphylococcus spp., Streptococcus spp., Klebsiella spp., Treponema spp., Enterobacter spp., Neisseria meningitidis, Neisseria gonorrfets, and of a number of a number of a number of of a few thousand years ago, a number of a number of ages and a few urealyticum, Mycoplasma spp., Rickettsia spp., Listeria monocytogenes, Escherichia coli, Typhus exanthematicus, Campylobacter fetus, Shigella spp. multocida, Actinomyces spp., Clostridium spp., Calymmatobacterium granulomatis, Fusobacterium fusiforme, Propionibacterium acnes, a number of protozoa (Plasmodium falciparum, Entamoeba spp.). In this case, the use of unidox will be almost useless for infections caused by Enterococcus spp., Acinetobacter spp., Pseudomonas spp., Proteus spp., Providencia spp., Serratia spp. Another problem that could potentially complicate treatment is the possibility of acquiring intragroup cross-resistance among tetracyclines (in other words, unidox-resistant strains will not respond to other tetracyclines and vice versa).
Food intake has virtually no effect on unidox absorption: in the gastrointestinal tract it is absorbed quickly and in full. The drug penetrates well into the tissue and 30-45 minutes after oral administration is already detected in most target organs and biological fluids. The drug is used in a variety of etiology and localization of infections: lesions of the respiratory tract, upper respiratory tract, urinary tract, digestive tract and biliary tract, soft tissue skin, as well as a number of other equally common bacterial "invasions".
Unidox should be taken during a meal. It is allowed to chew a tablet or divide it into pieces along the separation groove applied on it. The production technology of this dosage form provides for the dilution of the tablet in a small – about 20 ml – amount of water. The average duration of unidox is from 5 to 10 days. For adults and sufficiently well-fed (weighing more than 50 kg) children over 8 years of age, the daily dose of unidox is 200 mg for 1-2 doses on the first day, and then 100 mg daily. In severe cases, the dose is allowed to double. For children from 8 to 12 years old, whose body weight does not reach 50 kg, on the first day the dose is selected at the rate of 4 mg per 1 kg, and then – 2 mg per 1 kg.