Rigevidon and pregnancy

Description relevant to

Latin name: Rigevidon

  • ATH code: G03AA07
  • Active substance: Ethinyl estradiol + Levonorgestrel (Ethinylestradiol + Levonorgestrel)
  • Manufacturer: Gedeon Richter, Hungary
  • Additional ingredients: magnesium stearate, corn starch, povidone, talc, lactose monohydrate, colloidal silicon dioxide, sucrose, calcium carbonate, copovidone, titanium dioxide, macrogol 6000, carmellose sodium.

    Release form

    Available Rigavidon tablets, packaged in blisters of 21 pieces, 3 or 1 blister pack.

    pharmachologic effect

    Tablets Rigavidon show contraceptive act.

    Pharmacodynamics and pharmacokinetics

    This oral monophasic combined estrogen-progestin contraceptive drug can have a depressant effect on pituitary gonadotropic production hormones.

    In this case, the contraceptive effect is associated with several mechanisms. Progestin component progestin Includes a derivative of 19-nortestosterone known as levonorgestrel. This substance exceeds the activity of the corpus luteum hormone. progesterone or its synthetic analog pregnin, which has an effect at the receptor level, without being exposed metabolism.

    The estrogen component ethinyl estradiol leads to a blockade of the release of releasing hormones of the hypothalamus, inhibition of the production of gonadotropic hormones by the pituitary gland. At the same time, maturation and release of an egg cell ready for fertilization are inhibited.

    It is established that ethinyl estradiol enhances the contraceptive effect of the drug. Increased viscosity of the cervical mucus, which makes it difficult for sperm to penetrate.

    Also, regular use of the drug leads to the normalization of the menstrual cycle and prevents the development of certain gynecological diseases, for example, tumoral diseases.

    Inside the body, the drug undergoes rapid absorption. The concentration of Rigevidon depends on the dosage of the drug and the duration of use. The maximum concentration is usually detected after 2 hours, the elimination occurs on average for 16 hours. The drug is displayed in metabolites and unchanged by the bowels and kidneys.

    Indications for use

    The drug is recommended for:

    Rigevidon and pregnancy

    • oral contraception;
    • functional disorders of the menstrual cycle, for example, unidentified dysmenorrhea, dysfunctional metrorrhagia, premenstrual syndrome.

    Contraindications

    Contraceptive pills Rigevidon is not prescribed for:

    • drug sensitivity;
    • lactation, pregnancy;
    • severe liver disease;
    • congenital hyperbilirubinemia;
    • cholecystitis;
    • thromboembolism;
    • tumor diseases;
    • severe forms hypertension;
    • diabetes and other diseases of the endocrine glands;
    • sickle cellanemia;
    • chronic hemolytic anemia;
    • blistering;
    • age from 40 years;
    • migraine;
    • otosclerosis.

    Also, the drug is contraindicated to receive bleeding of various origin, idiopathic jaundice, pruritus and herpes in pregnant women.

    With care, Rigavidone is prescribed to patients with diseases of the liver, kidneys and gallbladder, epilepsy, depression, ulcerative colitis, uterine myoma, mastopathy, tuberculosis, diseases of the cardiovascular system, arterial hypertension, impaired renal function, phlebitis varicose veins, otosclerosis and multiple sclerosis. Also, caution is required when prescribing pills to patients in adolescence.

    Rigevidon during pregnancy and lactation

    It is established that during pregnancy and lactation the use of this drug is contraindicated.

    Side effects of Rigavidon

    Typically, this drug is well tolerated by patients, but sometimes side effects of rigevidon occur, which develop transiently and pass spontaneously. For example, nausea, vomiting, headaches, weight gain and libido change, mood, manifestation of acyclic bleeding, conjunctivitis, vision problems and so on.

    In rare cases, prolonged use of the drug causes chloasma, hearing loss, jaundice, generalized itch, convulsions, frequency of epileptic seizures, hypertriglyceridemia, hyperglycemia, increased pressure, thrombosis or venous thromboembolism, rash on the skin, changes in vaginal secretion, high fatigue, vaginal candidiasis And so on.

    Rygevidon tablets, instructions for use (method and dosage)

    Instructions for use Rigevidon recommends taking the pill inside, completely with water.

    When the previous menstrual cycle did not perform hormonal contraception, then it should be started on the 1st day of menstruation. Then you need to take one pill every day for 21 days, preferably at a certain time of day.

    After that, spend a break of 7 days, during which menstrual bleeding occurs. For the next 21 days, tablets are taken from a new package, that is, on the 8th day, regardless of whether the bleeding has stopped or not.

    Switching to these pills from another contraceptive is carried out in the same way. You can take the drug until it is necessary.

    Taking the drug after abortion You can start immediately on the day of surgery or the next day. After birth, the contraceptive is allowed for use by women who do not feed the baby. Start his reception should be from the first day menses.

    When skipping pills, it is important to know how to take Rigevidon in such cases. According to the instructions, the missed pill must be taken in the next 12 hours. If after taking the drug it takes more than 36 hours, then contraception will be unreliable, so you need to take care of additional contraceptives.

    The use of the drug for therapeutic purposes requires an individual selection of the dosage and therapeutic scheme.

    Overdose

    Cases of overdose Rigavidonom not noted.

    Interaction

    Combination with barbiturates, antiepileptic drugs, for example, Carbamazepine and Phenytoin, as well as sulfonamides, derivatives of pyrazolone can lead to increased metabolism steroid hormones, included in the preparation.

    The combined use of Rigavidone and some antimicrobial agents is able to reduce the contraceptive effect: Ampicillin, Rifampicin, Chloramphenicol, Neomycin, Polymyxin B, sulfonamides and Tetracycline, as they change the composition microflora intestine.

    This drug may increase the bioavailability and toxicity of tricyclic antidepressants, beta-blockers and Maprotiline, reduce efficiency Bromocriptine.

    Joint reception with hypoglycemic drugs and insulin often requires changing their dosing. When taking with the drug Dantrolene it is possible that its hepatotoxicity will increase, mainly in women from 35 years of age.

    special instructions

    Before starting to take contraceptive pills, and every six months when they are used, it is necessary to undergo a general medical and gynecological examination. It usually includes cytology, breast exam, blood glucose score, cholesterol, liver function, pressure and urine composition.

    Patients who have suffered viral hepatitis and they have normalized liver function, the drug is prescribed not earlier than 6 months from the moment of recovery.

    If there is a sharp pain in the abdominal cavity, hepatomegaly and signs intra-abdominal bleeding, then it may indicate a liver tumor. If necessary, the drug is immediately canceled.

    Appearance intermenstrual bleeding does not require the cancellation of the contraceptive, as they usually stop on their own. When this does not occur, consultation of the gynecologist is necessary.

    As you know, women who smoke when taking hormonal contraceptives can develop vascular diseases with serious consequences – myocardial infarction and stroke

    Terms of sale

    Storage conditions

    Store Ripevidon should be at room temperature, out of the reach of children.

    Shelf life

    Analogues of Rigevidon

    Basic analogues: Yarin, Regulon and Janine.

    Rigevidon or Regulon – which is better?

    To understand which of these drugs is better, you just need to compare Rigividon and Regulon. Their main difference lies in the progestin component – in Regulon it is desogestrel, which also does not have an anti-androgenic effect. At the same time, before taking these pills, it is difficult to understand how they are suitable and how they will be tolerated by patients.

    There are many reviews when women took one of these drugs for a long time. This did not lead to undesirable effects, such as a change in libido or weight gain. Moreover, immediately after the cancellation of these contraceptives, pregnancy almost immediately began. Therefore, the selection of such drugs must be performed taking into account the individual characteristics after consultation with the gynecologist.

    Alcohol and Rigavidone

    Cases of reduced efficacy of this drug, when alcohol is consumed in large quantities.

    Reviews Rigavidone

    Many women of reproductive age take various contraceptive drugs. Therefore, you can find reviews about Rigavidone in forums where women are actively discussing such means.

    Rigevidon and pregnancy

    Of course, the attitude towards them is completely different. Some believe that birth control pills carry only benefits and willingly take them. Others, on the contrary, are afraid of using any hormonal drugs and therefore use other methods of contraception, which are not always effective. Also there are messages when users do not know from what pills and why they are taken.

    Women who have experienced this drug on themselves, also express completely different opinions. Some patients report that during his reception they experienced constant nausea, mood changes and gained considerable weight. However, many women say that they take Rigevidon 21 + 7 for several years and during all this time they have not experienced any unwanted effects. In this case, the drug provides them with reliable protection against unwanted pregnancy.

    Special attention should be paid to the reviews of doctors who use different drugs in their practice. They once again note that the choice of such funds should not pass on their own. If you need contraception, you can always consult a gynecologist for a full examination, determine the hormonal status, discuss plans for pregnancy and choose the appropriate method of protection against unwanted conception.

    Price Rigavidon where to buy

    The price of Rigevidon in pharmacies varies between 200-650 rubles.

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