Pain relievers during pregnancy

Ketoprofen belongs to the group of nonsteroidal anti-inflammatory drugs and is a derivative of propinoic acid.

Ketoprofen’s anti-inflammatory effect is on par with Indomethacin and Naproxen and is superior to the anti-inflammatory effect of Ibuprofen and Aspirin. The analgesic effect of Ketoprofen is similar to the effect of Indomethacin and Naproxen.

Pharmacological effects

Ketoprofen helps to provide analgesic, antipyretic and anti-inflammatory effects. Anti-inflammatory action can be achieved after 7 days of oral administration of the drug.

In that case, if the drug is used for the treatment of articular syndrome, Ketoprofen will help eliminate pain syndrome at rest, and when moving, will eliminate symptoms such as morning stiffness and swelling of the joint. Against the background of the use of the drug, an increase in mobility is observed.

Ketoprofen gel helps to provide a local anesthetic effect. With local use, the concentration of the active ingredient is maintained for a long period of time at the site of inflammation.

Release form, composition

The drug Ketoprofen is available in the form of tablets forte, retard tablets, capsules, gel, suppositories, solution for injection, cream.

• Capsules contain 50 mg of the active ingredient. • Forte tablets contain 100 mg of the active ingredient. • Retard tablets contain 150 mg of the active substance. This form of the drug has a prolonged effect that allows you to take pills only once a day. • The composition of the gel (1 gram) contains 25 mg of the active substance. • The composition of the solution for injection contains 50 mg of component (per 1 ml of the drug). • The cream (in 1 gram) contains 50 mg of the active substance. • Suppositories contain 100 mg of the active substance.

Selection of a particular form of the drug Ketoprofen is carried out by a doctor, depending on the indications for use of the drug and the accompanying symptoms.

Indications for use

Indications for use of the drug Ketoprofen for systemic use (orally, intravenously, rectally, intramuscularly) are the following states:

• Combination therapy of inflammatory and degenerative diseases (rheumatoid arthritis, nonspecific spondyloarthritis, gouty arthritis, pseudogout, osteoarthrosis, bursitis, tenosynovitis). • Elimination of intense painful sensations of various origins, including postoperative and post-traumatic pain, sciatica, myalgia, sciatica therapy, bruises and muscle sprain, renal colic. • The drug is used in dentistry and gynecology (including, for primary dysmenorrhea). • Intravenous Ketoprofen is used to eliminate pain in diseases of the musculoskeletal system.

Ketoprofen for external use is used:

• In the complex treatment of acute and chronic diseases of the musculoskeletal system, including rheumatoid arthritis, arthrosis, osteochondrosis. • With painful traumatic or inflammatory lesions of the joints, ligaments, tendons: arthritis, muscle injuries, bursitis, sprain and ligament rupture, dislocations. • In the treatment of phlebitis, thrombophlebitis, inflammatory diseases of the skin.


Ketoprofen is not recommended for use with individual intolerance to the active or auxiliary substances of the drug.

Contraindications to systemic use are the following conditions: the presence of gastric ulcer or duodenal ulcer, “aspirin” asthma, ulcerative colitis in the acute stage, Crohn’s disease, peptic ulcers, bleeding disorders. The drug is not used in renal and hepatic failure, as well as in children under 18 years of age and in the third trimester of pregnancy.

Suppositories are not recommended for use in hemorrhoids, proctitis, proctorragia.

Ketoprofen gel and cream is not used for oozing dermatoses, eczema, infected abrasions, violations of the integrity of the skin, in children under 6 years of age.

Adverse reactions

Ketoprofen can contribute to the development of such side effects. Central nervous system: may develop headache, nervousness, dizziness, insomnia, strange dreams, drowsiness, malaise, tinnitus, visual impairment, general malaise.

Cardiovascular system: increased blood pressure, increased heart rate, the development of peripheral vascular disease, anemia, thrombocytopenia.

Gastrointestinal tract: some patients may complain of nausea, constipation, flatulence, pain in the abdomen. In rare cases, the formation of stomatitis, vomiting, increased appetite, dry mouth, rectal bleeding, increased salivation, hidden bleeding was noted.

Respiratory system: the development of nasal bleeding, bronchospasm, pharyngitis, rhinitis, laryngeal edema.

Skin: the development of allergic reactions in the form of a rash, feelings of itching and burning, redness of the skin, alopecia, oncholysis, bullous rash, toxic epidermal necrolysis.

Other adverse reactions associated with the occurrence of chills, swelling of the face, weight gain.

In the event that Ketoprofen causes the described or any other side effects, the use of the drug should be discontinued. You may need to reduce the dosage or replace the medication, at the discretion of the treating physician.


With an overdose of the drug may develop dizziness, lethargy, vomiting, nausea, abdominal pain. Side effects are reversible. As treatment, it is necessary to flush the stomach, to conduct symptomatic and supportive therapy. Additionally, you must monitor the state of the respiratory and cardiovascular systems.

Mode of application

Ketoprofen is intended for internal, intramuscular, intravenous, rectal, epidermal, and topical use. The dosage and method of administration are selected individually, taking into account the severity of the disease and associated symptoms.

Pain relievers during pregnancy

As required, allowed to combine several dosage forms of the drug. The appointment of the drug and the selection of the dosage should be done only by a doctor! Infusions with the use of the drug should be carried out only in stationary conditions.

Ketoprofen in the form of tablets, capsules and granules must be taken during or after the main meal. This avoids the development of side effects from the gastrointestinal tract.

Additional recommendations

The use of Ketoprofen medication is possible with extreme caution and only under medical supervision if the patient is allergic to drugs of aspirin row, peptic ulcer, diabetes, anemia, alcoholism, renal and chronic heart failure, high blood pressure.

If a patient has a history of allergic reactions, the use of non-steroidal anti-inflammatory drugs, including Ketoprofen, is possible only in extreme cases.

Using Ketoprofen may help mask the symptoms of various infectious diseases.

When used externally, do not allow the drug to get into the eyes, on damaged skin and mucous membranes.

When using the drug by patients whose activities require increased attention and concentration, it should be remembered that Ketoprofen can influence the reaction rate.

Cost, analogues

The cost of Ketoprofen for January-February 2015 is formed as follows:

Pain relievers during pregnancy

• Ketoprofen gel external, 30 grams (Russia) – 45-50 rubles. • Gel outer, 50 grams (Russia) – 60-70 rubles.

The following drugs are analogues of Ketoprofen: Ketonal, Bystrumgel, Artrum, Artrozilen, Fastum gel, Flamax, Flexen.

Patient reviews about medication

“Ketoprofen bought her grandmother after she bruised her knee. The drug is inexpensive and did not pin special hopes on it. It was a surprise when, after applying the gel, the anesthetic effect came literally within 5 minutes. No side effects have arisen. They say that it is better to combine the gel with tablets, but we do not risk, because grandma has problems with the gastrointestinal tract. “

“Recently I fell a lot on the tailbone and any movement caused severe pain. The pharmacy advised to use Ketoprofenom. Immediately bought the drug, because it is quite inexpensive. There was no time to read the instructions or go to the doctors. Put a little on the sore spot. I can not say anything, the analgesic effect began almost immediately.

But at the same time there were side effects! I applied the drug twice a day: in the morning and evening, and on the third day, a rash appeared in the place of application in the form of small blisters. Immediately stopped treatment with the drug and the rash was gone. Now I’m wondering if the medicine can be used further. ”

“I used Ketoprofen for back pain on the advice of a doctor. Pain syndrome passed almost immediately. But at the same time she did some physical exercise and took Arthra.

In the complex, all drugs had the desired effect. In particular, Ketoprofenom is very pleased, there were no side effects. When she took only Arru, she did not have the necessary analgesic effect. ”

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