Nasonex during pregnancy

In this article, you can read the instructions for use of the drug. Nasobek. Presented reviews of visitors to the site – the consumers of this medicine, as well as the opinions of doctors of specialists on the use of Nasobek in their practice. A big request to add your feedback on the drug more actively: the medicine helped or did not help to get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogs of Nasobek in the presence of available structural analogues. Use for the treatment of allergic rhinitis and vasomotor rhinitis in adults, children, as well as during pregnancy and lactation. The composition of the hormonal drug.

Nasobek – synthetic glucocorticosteroid (GCS) for local use. It has anti-inflammatory, anti-allergic and immunosuppressive effects. Increases the production of lipomodulin, which is an inhibitor of phospholipase A, inhibits the release of arachidonic acid. It prevents the regional accumulation of neutrophils, reduces inflammatory exudation and production of lymphokines, inhibits the migration of macrophages, reduces the intensity of the processes of infiltration and granulation, the formation of chemotaxis substance. Reduces swelling of the nasal mucosa, mucus production. Improves mucociliary transport.

The drug is well tolerated with long-term treatment, does not possess mineralocorticoid activity, and has practically no resorptive effect.


Beclomethasone dipropionate + excipients.


When inhalation method of administration in recommended doses does not have significant systemic activity. After intranasal (in the nose) application is rapidly absorbed through the nasal mucosa. A part of the injected drug is swallowed. Absorption from the gastrointestinal tract is low. Plasma protein binding – 87%. Most of the drug trapped in the digestive tract is metabolized by "first pass" through the liver. The main part of the drug (35-76%), regardless of the method of administration, is excreted within 96 hours with feces, mainly in the form of polar metabolites; 10-15% excreted by the kidneys.


  • seasonal and year-round allergic rhinitis;
  • vasomotor rhinitis.

Forms of release

Spray nasal dosed.

Dosage form in the form of nasal drops does not exist.

Instructions for use and method of use

The drug is used intranasally.

Adults and children over 12 years old are prescribed 50-100 mcg (1-2 doses) in each nasal passage 2 times a day; the daily dose is 200-400 mcg. The maximum daily dose is 400 micrograms. The daily dose can be divided into 2-4 doses.

Children from 6 to 12 years old are prescribed in an initial dose of 50 µg (1 dose) in each nasal passage 2 times a day, if necessary – 100 µg (2 doses) in each nasal passage 2 times a day. The maximum daily dose is 400 micrograms. The daily dose can be divided into 2-4 doses.

When a therapeutic effect is achieved, the drug is canceled, gradually reducing the dose.

Elderly patients dose adjustment is not required.

Terms of use of the drug

Before using the drug, you must clean the nasal passages.

When using for the first time, the spraying mechanism should be unlocked: press the dispenser several times until the aerosol cloud appears. If the drug has not been used for several days, the spraying mechanism should be unlocked again.

Before the first use of the drug, remove the plastic protective half-ring between the screw part and the dispensing nasal applicator.

  1. Before use, shake the bottle slightly, then remove the cap of the nasal applicator.
  2. Position the bottle between the thumb and index fingers so that the bottom of the bottle rests on the thumb, and the index and middle fingers rest on both opposite sides of the bottom of the applicator.
  3. Before the first use of the drug, or in the case of a long interruption in use, the first dose should be sprayed into the air.
  4. Exhale slightly through the nose.
  5. The nasal passage, in which the drug will not be injected, should be clamped with a finger, and the applicator should be inserted into the free nasal passage. Then slightly bow your head so that the vial is in a perpendicular position.
  6. Inhale slightly through the open nasal passage and simultaneously press the nasal applicator and inject the aerosol dose.
  7. Exhale through the mouth.
  8. With repeated administration of the drug in the same nasal passage, the steps described in paragraphs 6 and 7 should be repeated.

With the introduction of the drug in another nasal passage, you should repeat the steps described in paragraphs 5, 6, 7, 8.

After the end of the application of the drug, the end (top) part of the applicator should be cleaned with a clean cloth and the cap should be replaced.

Nasonex during pregnancy

The nasal applicator should be cleaned at least 1 time per week to prevent the possibility of clogging. To do this, slightly press the bottom of the applicator and disconnect the nasal applicator. Rinse the applicator and cap with warm water and allow to dry. After that, put the applicator and cap back on the bottle.

Side effect

  • skin rash;
  • hives;
  • angioedema;
  • violation of olfactory and taste sensations;
  • drowsiness;
  • headache;
  • dizziness;
  • increased intraocular pressure;
  • glaucoma;
  • cataract (with prolonged use);
  • conjunctival hyperemia;
  • reduced vision;
  • dryness and irritation of the nasopharynx;
  • sneeze;
  • burning, nasal congestion;
  • bleeding from the nose;
  • atrophy of the nasal mucosa;
  • cough;
  • rhinorrhea;
  • ulceration of the nasal mucosa;
  • perforation of the nasal septum (usually in patients who have previously undergone surgery in the nasal cavity);
  • myalgia;
  • candidiasis of the mouth and upper respiratory tract;
  • with prolonged use may develop adrenal insufficiency, a decrease in the growth rate in children, a decrease in bone mineral density.


  • hemorrhagic diathesis;
  • frequent nosebleeds;
  • respiratory tuberculosis;
  • fungal infections;
  • viral infections;
  • children up to 6 years;
  • 1 trimester of pregnancy;
  • hypersensitivity to the drug.

Use during pregnancy and lactation

The use of the drug Nasobek is contraindicated in the first trimester of pregnancy. The use of the drug Nasobek in 2 and 3 trimesters of pregnancy is allowed only if the expected benefit to the mother exceeds the possible risk to the fetus.

Use the drug Nasobek during the breastfeeding period should be with caution.

Use in children

Contraindicated in children under the age of 6 years.

With prolonged use of the drug Nasobek in children, it is necessary to control the dynamics of their growth.

special instructions

Patients should be warned about the need to be careful and not to get into the eyes of the drug Nasobek.

The therapeutic effect of the drug Nazobek, in contrast to the local vasoconstrictor drugs for the treatment of rhinitis, with intranasal use is not immediately apparent. Relieving the symptoms of rhinitis usually becomes noticeable after 5-7 days from the start of the drug. When a therapeutic effect is achieved, the dose of Nazobek should be reduced to the minimum effective dose controlling the course of the disease.

Patients with a high risk of developing adrenal insufficiency will need medical supervision.

Since the drug slows down the healing of wounds, patients with ulceration of the nasal septum, after surgical interventions in the nasal cavity, nasal injuries, should not use the preparation Nasobek until the wounds are fully healed.

When infectious diseases of the nasal cavity and paranasal sinuses should be appropriate therapy. These diseases are not contraindications to the use of the drug Nasobek.

Benzalkoniya chloride contained in the preparation Nasobek, with prolonged use increases the risk of edema of the nasal mucosa. If a similar reaction occurs, a dose adjustment of Nasobec ​​or the use of a drug that does not contain benzalkonium chloride is necessary.

Influence on ability to drive motor transport and control mechanisms

Due to the fact that the use of the drug Nasobek may develop drowsiness and dizziness, patients should be careful when driving and occupations of potentially hazardous activities that require high concentration of attention and psychomotor reactions.

Drug interaction

When combined, phenobarbital, phenytoin, rifampicin reduce the effectiveness of beclomethasone (induction of microsomal oxidation enzymes).

When combined, methandrostenolone, estrogen, beta2-adrenomimetiki, theophylline, GCS for oral administration increase the effect of beclomethasone.

When combined, Nasobek enhances the effect of beta adrenomimetics.

Analogues of the drug Nazobek

Structural analogues of the active substance:

  • Aldecine;
  • Beclazon;
  • Beklat;
  • Becklodget 250;
  • Beclomet Icheheiler;
  • Beclomethasone;
  • Beklospir;
  • Becolfort;
  • Baconase;
  • Bekotid;
  • Klenil;
  • Plibekot;
  • Rynoklenil.

Analogs for the therapeutic effect (means for the treatment of vasomotor and allergic rhinitis):

  • Avamys;
  • Aqualore software;
  • Allerhoferon;
  • Aldecine;
  • Vibrocil;
  • Vividrin;
  • Galazolin;
  • Histaglobin;
  • Histaglobulin dry;
  • Hisalong;
  • Histaphin;
  • Histimette;
  • Grippostad Reno;
  • Dexamethasone;
  • Derinat;
  • Diprospan;
  • For carrying;
  • Dr. Theiss Nazolin;
  • Zaditen;
  • Zodak;
  • Immunoglobulin antiallergic liquid;
  • Intal;
  • Rec 19;
  • Claritin;
  • Clemastine;
  • Kromoglin;
  • Cromolin;
  • Xylene;
  • Xylometazoline;
  • Loratadine;
  • Lordaestin;
  • Morenazal;
  • Nazivin;
  • Nazol;
  • Nasonex;
  • Naphthyzinum;
  • Parlazin;
  • Pinosol;
  • Polyoxidonium;
  • Prednisolone;
  • Rhinital;
  • Rinonorm;
  • Sanorin;
  • Snoop;
  • Suprastin;
  • Tavegil;
  • Telfast;
  • Tizin;
  • Phenystyle;
  • Fencarol;
  • Physiomer nasal spray;
  • Fliksonaze;
  • Cetirinax;
  • Tsetrin;
  • Erbisol;
  • Erolin.
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