In the life of many women, an unplanned pregnancy occurs, requiring a responsible and difficult decision. In order to avoid mechanical abortion, one should pay attention to the drug option, for the implementation of which special preparations are used.
One of them is Cytotec, used in gynecology for termination of pregnancy (if the delay does not exceed 42 days).
Indications for use
The drug is effective as a preventive measure with a tendency to diseases of the gastrointestinal tract, to prevent the development of ulcers, erosive forms of gastritis. The drug allows you to maintain the integrity of the mucous organs of the digestive system, suppressing the synthesis of pepsin, accelerates the scarring of erosions of the mucous by reducing the volume of hydrochloric acid produced by the stomach during the night, stimulates contractions of the muscles of the intestine.
In gynecology, pills are used to terminate pregnancy at the final stage of medical abortion. The use of the drug provokes samoabort (miscarriage), which allows to avoid unwanted and dangerous surgical procedure. The need to take drugs that stimulate the release of the ovum from the uterus by increasing contractions of the myometrium can be caused by a frozen pregnancy or used as an alternative to surgical “cleansing” with incomplete abortion. Cytotec is effective when used with Mifepristone – a combination of drugs allows you to achieve your goal – abortion.
The composition of the drug
The main active substance contained in the pills – Misoprostol dosage
Cytotec – synthesized artificially prostaglandin E1. The action of the tablets is aimed at suppressing the secretory function of the stomach, as a result of which the production of hydrochloric acid is reduced and an increased secretion of mucus occurs, promoting healing of erosions and ulcers. The protective function is confirmed clinically, so the drug is prescribed to patients with certain diseases of the gastrointestinal tract.
In gynecology, Cytotec is used to improve the tone of the uterus, which occurs due to the rapid contraction of the muscles of the myometrium. The drug provokes spontaneous dilation of the cervical canal, facilitating the release of the ovum.
Forms of release
The cost reaches 1300 – 2850 Russian rubles and depends on the number of tablets per pack.
Cytotec is produced in the form of tablets of white color of a cylindrical flat form with a notch in 1/2/3/5 blisters of 10 pieces, packed in a cardboard box. The dosage of the main active ingredient, misoprostol, is 200 μg.
Mode of application
Method of administration and dosage of the drug is calculated on the basis of the therapeutic goal.
In the treatment of gastric or duodenal ulcers CytoTEC instructions for use indicate the need to take 1 tablet 2-4 times a day. The last dose of medication is recommended to drink before bedtime to increase efficiency and inhibit the production of excess amount of gastric juice.
The desired effect of medical abortion is achieved by combining two drugs – Mifepristone and Cytotec. Use the drug should be in a specialized medical institution under the watchful supervision of a gynecologist. Initially, the patient is prescribed Mifepristone; after 24 hours – two tablets Sitekit. The dose of the drug is calculated by the doctor, based on the approximate dose for a single use (200 mg) and the individual characteristics of the patient (age, weight, presence in the history of childbirth / abortion). The onset of action of the drug is observed after half an hour; The period of complete disintegration in the body is 6 hours. The visible effects of pharmacological effects on the woman’s body are cramping pain in the lower abdomen, followed by severe bleeding, indicating the release of the ovum. In women who took pills, the duration of bloody discharge from the vagina periodically reached 7-14 days.
The procedure is recommended if the gestation period does not exceed 6 weeks (up to 42 days delay). Legislation strictly forbids the use of pills in the later stages of pregnancy.
Oral administration of Cytotec tablets is the final stage of abortion. The success of the procedure should be monitored during the week after passing an ultrasound examination. The next menstruation after using Cytoteca comes about in a month.
During pregnancy and breastfeeding
The drug has a group of contraindications, which are presented in detail in the instructions. Cytotec is prohibited to use:
- Pregnant women who want to safely carry the baby
- During lactation (breastfeeding)
- To abort ectopic pregnancy.
After reviewing the instructions, it is worth considering the following: taking the drug is incompatible with the presence of the patient’s diseases:
- Of cardio-vascular system
- Intestinal tract inflammation
- Of the liver.
The use of Cytotec for minors and women using a certain type of contraception (IUDs, rings) is contraindicated.
Strict medical supervision while taking the drug is recommended for the following individuals:
- Suffering from bronchial asthma
- Kidney disease
Taking drugs belonging to the pharmacological group of antacids may be accompanied by diarrhea and a decrease in the concentration of the active ingredient Cytotec. Against the background of a combination with Indomethacin, Diclofenac and magnesium-containing drugs, an increase in the side effects of these drugs was observed.
The use of alcohol against the background of Cytotec use is completely excluded, as is the parallel intake of psychotropic medications. There is a decrease in response, so you should devote the next 6 hours to rest, avoiding processes that require concentration (driving, some types of work).
Despite the relatively mild effect, Cytotec tablets for abortion may be accompanied by the following side effects:
- Disorders of the gastric intestinal tract (diarrhea, nausea, flatulence)
- Disorders of the cardiovascular system
- Sharp weight fluctuations amid hormonal disorders
- Allergic reactions
- Menstrual disorders
- Uterine bleeding
- Migraines, headaches, drowsiness, low blood pressure
- The threat of infertility.
Symptomatic treatment may be required to eliminate the negative effects of the drug, however, in most cases, the unpleasant symptoms disappear within 4-9 hours, which is explained by a gradual decrease in the concentration of prostaglandin.
An overdose of the drug does not cause irreversible changes in the female body. It is manifested by the following symptoms:
- Fever, tremor, convulsions
- Pulling pains in the iliac region.
Terms and conditions of storage
Cytotec tablets are stored in a dry place inaccessible to children, subject to a temperature regime not higher than 30 ° C for up to 3 years.
Analogues Cytotec are the following medications:
China Beijing Zizhu Pharmacetical
A drug that is also an anti-ulcer medicine and is used to stimulate uterine contractions. The price of the drug – from 3000 Russian rubles. Tablets are white, round, packaged in pieces in 1 blister and carton.
- Non-toxic for the body to avoid overdose
- Carefully investigated pharmacological action.
- The spectrum of side effects is more pronounced in comparison with Cytotec
- Misoprostol is difficult to purchase (its analogues are often used)
- Possible intolerance to the drug.
Russia CJSC Obninsk Chemical Pharmaceutical Company
The active ingredient of the drug is also misoprostol. Flat tablets of a cylindrical shape of a yellow or gray shade are packed into blisters or banks from polymer in the amount of 4/10/20/30 pieces. The action of the drug is aimed at stimulating contractions of the uterine myometrium, which provokes the onset of labor. The cost of Mirolyut (10 tablets) reaches 1200-1500 Russian rubles.
- Relatively low cost of medication
- High rate of half-life and withdrawal from the body.
- An impressive range of side effects and drugs of cross-interaction
- The need for use in conjunction with other drugs of similar pharmacological action.