It can be considered a complete analogue of methylprednisolone.
Average online price * 37 r. (pack of 3 ampoules)
Where can one buy:
Instructions for use
Prednisolone (Prednisolonum) is a synthetic drug belonging to the group of glucocorticosteroids.
Available in several dosage forms: ointment, tablets and injections.
Antiallergic, anti-inflammatory, immunosuppressive agent, superior in activity to cortisone, and hydrocortisone 3-4 times. Analogs are: dekretin, medopred, inflanafran, prednisol, prelnigexal.
Prednisolone Injection is a colorless (or yellowish) water soluble substance.
Available in ampoules, sealed in cartons of 3,5,6,10 and 20 pieces (30 mg of prednisone sodium phosphate / 1 ml solution for injection).
The drug for intravenous or intramuscular administration, refers primarily to the means of emergency care, used in the following cases:
- with severe allergic reactions (angioedema, anaphylactic shock, an attack of bronchial asthma);
- in case of acute renal-hepatic failure, which developed in the postoperative or postpartum period;
- with severe rheumatic fever;
- shock condition (cardiogenic, burn, traumatic shock);
- swelling of the brain;
- in acute hepatitis;
- in acute adrenal insufficiency
- in case of poisoning with aggressive liquids causing burns to the mucous membranes.
In addition to emergency care, the drug is used in complex therapy in the treatment of malignant tumor processes, autoimmune, chronic pulmonary and dermatological diseases.
Indications for the use of prednisolone are also some cardiac pathologies, in particular, exudative pericarditis and rheumatoid myocarditis, as well as a decrease in threshold excitation in patients with an implanted heart stimulator.
The drug is used in hematology – in the treatment of leukemia, anemia, MDS, pathologies associated with bone marrow dysfunctions.
Many patients, far from medicine, believe that “hormonal” drugs cause irreparable harm to the body, and therefore either stop taking it prematurely or do not take the medicine at all.
Such an approach may, in some cases, lead to dire consequences, many of which are irreversible.
With a correctly calculated dosage, prescribed by a specialist, taking into account the indications and state of health, the drug will not cause serious complications. Remember that absolutely all drugs (including those of natural origin) have side effects that are much more serious than those that cause corticosteroids. Therefore, you should take prednisone (medopred) precisely according to the scheme, which was made by the attending physician.
Dosage and duration of treatment is prescribed individually.
Standard dosage for adults:
at the beginning of treatment, depending on the severity of the disease, 25–100 mg / day,
in the subsequent 25-50 mg / day.
In severe cases, the dose may be increased.
Children 6-12 years old in / in or in / m 25 mg / day,
from 12 years old – 25-50 mg / day.
The following treatment regimen is generalized because it does not take into account the patient’s health status and the presence of relative contraindications:
with acute adrenal insufficiency – from 100 mg to 200 mg once a day, for 3-14 days;
in the treatment of bronchial asthma – from 75 mg to 675 mg per treatment course (from 3 to 16 days);
in shock, accompanied by a drop in blood pressure jet injected 50-150 mg, in severe cases, the dose is increased to 400 mg (the maximum daily dose is 1000 mg);
with complications after surgery and acute poisoning, the drug is administered at 25-75 mg per day (in severe cases, increase to 300-1500 mg per day).
for rheumatoid arthritis shown from 75-125 mg per day for a course of treatment for 10 days;
with severe hepatitis designate 75-100 mg per day for a course of treatment, calculated on 7-10 days;
with internal burns respiratory and digestive organs from 75 to 400 mg per day for 5-18 days.
If the drug cannot be administered intravenously, intramuscular injections are prescribed. After stabilization of the state, prednisone is prescribed in capsules (tablets) with a gradual decrease in dose.
There is still intraarticular introduction, but it is conducted only by a doctor, the dosages are selected only individually for each patient.
In case of emergency (shock) conditions, prednisone is administered without taking into account contraindications, as a means of emergency care.
Do not use the drug in therapeutic courses for severe hypertension, gastric ulcer and duodenal ulcer, reflux disease, osteoporosis, Cushing’s disease.
Contraindications are infections such as chickenpox, herpes, shingles, as well as the active form of tuberculosis, pregnancy (first trimester, in particular), lactation.
Use during pregnancy and breastfeeding
Like all corticosteroids, prednisone is categorized as C by the FDA.
This means that adequate and strictly controlled studies of the safety of use in pregnant women have not been conducted. The drug penetrates through the placenta. There are proven teratogenic effects, possibly the development of adrenal insufficiency in the fetus and newborn.
Unfortunately, in some situations, corticosteroids have to be used to save the expectant mother. The decision on their appointment should be made by the doctor, informing the patient.
Nursing women are advised to stop breastfeeding at the time of treatment.
Corticosteroids penetrate into breast milk and can inhibit the growth, production of their own hormones and cause unwanted effects in the newborn.
Compatibility with alcohol
Alcohol in combination with prednisone increases the risk of developing peptic ulcer and bleeding from the gastrointestinal tract.
Weight gain, potassium deficiency (hypokalemia), growth retardation in children, Cushing syndrome (moon face), increased blood pressure, thrombosis, muscular atrophy, thinning of the skin, a violation of the digestive process, nausea.
On the part of the nervous system, such manifestations as depression, hallucinations, reduced visual acuity, general weakness, and headache are possible.
The above symptoms are possible, but they do not appear in every case. In general, the drug is well tolerated by patients, even with prolonged use.
The drug is not recommended to take simultaneously with salicylates, barbiturates, diuretics, cardiac glycosides. When taking medication, it is necessary to monitor blood pressure indicators, donate blood for sugar, examine feces for occult blood, make an x-ray (for arthritis and bursitis).
When intravenous prednisone is administered, the effect occurs immediately, a little slower with intramuscular injections. The drug binds to plasma proteins (globulins and albumin), is metabolized in the liver (mostly), and in the kidneys. Duration of exposure 24-36 hours.
Terms of sale
The drug is available on prescription.
(Leave your feedback in the comments)
[su_quote cite = “Anna,
[su_quote cite = “Rimma,
[su_quote cite = “Svetlana, Vladivostok”] My daughter is 16 years old. Since childhood, she suffers from allergic rhinitis. No procedures and drugs helped, including imported, expensive means. They recommend changing the climate, but we do not have the opportunity to move to another region. Doctors prescribed therapy, including a gentle course of prednisone. I do not know what will happen next, but so far she feels fine, and there were no complications. [/ su_quote]
* – The average value among several sellers at the time of monitoring is not a public offer.