Glutamic acid for children

The composition of the drug:

1 tablet contains:

excipients: croscarmellose sodium; mannitol (E 421), magnesium stearate;

casing: Opadry 200 White film coating mixture: talc, polyvinyl alcohol, titanium dioxide (E 171), polyvinyl acetate phthalate, glycerol monostearate, sodium lauryl sulfate, sodium bicarbonate; mixture for film coating Opadry II Yellow: polydextrose, talc, quinoline yellow aluminum varnish (E 104), hypromellose, maltodextrin, medium chain triglycerides, titanium dioxide (E 171).

Dosage form. Tablets, film coated.

Round-shaped tablets with a biconvex surface, covered with a yellow film coating. Have a characteristic smell.

Multivitamin preparations with other additives. ATC code А11А V.

Vitamin A (retinol acetate) plays a key role in the synthesis of protein enzymes and structural components of tissues, is necessary for the formation of epithelial cells, bones and rhodopsin synthesis, supports the division of immunocompetent cells, the normal synthesis of immunoglobulins and other infection protection factors.

Vitamin E (α-tocopherol acetate) is a physiological antioxidant that protects cell membranes from damage, stimulates the synthesis of heme and many proteins.

Vitamin B1 (thiamine hydrochloride) – an important coenzyme in the metabolism of carbohydrates, is involved in the functioning of the nervous system.

Vitamin B2 (riboflavin) is part of the flavin coenzymes – flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are involved in redox reactions, and is a catalyst for cellular respiration.

Vitamin B6 (pyridoxine hydrochloride) plays an important role in the metabolism of amino acids, neurotransmitters and hemoglobin.

Vitamin B12 (cyanocobalamin) is a growth factor, necessary for the normal course of the blood formation and maturation of red blood cells, is involved in the synthesis of amino acids, nucleic acids and myelin.

Nicotinamide – a component of the cofactor NAD (H) and NADP (H), part of the glucose tolerance factor, is involved in the processes of tissue respiration, carbohydrate and lipid metabolism.

Folic acid is essential for the normal formation of blood cells; together with vitamin B12 stimulates erythropoiesis, takes part in the synthesis of amino acids, nucleic acids, in the metabolism of choline.

Vitamin C (ascorbic acid) is involved in redox processes, essential for the growth and formation of bones, skin, teeth, capillary endothelium and for the normal functioning of the nervous and immune systems.

Rutin reduces capillary permeability and fragility, takes part in redox processes, inhibits the action of hyaluronidase.

Calcium D-pantothenate is a part of coenzyme A, it is necessary for normal functioning of the tricarboxylic acid cycle, ATP synthesis, production of hormones and antibodies, acetylcholine synthesis, assimilation of potassium, glucose, vitamin E from the intestine.

Copper is an essential trace element that is actively involved in iron metabolism, hemoglobin synthesis, reticulocyte maturation, and anabolic processes.

Potassium is involved in electrolyte metabolism, conducting nerve impulses.

Fitin is a complex organic compound of phosphorus containing a mixture of calcium and magnesium salts of inositol phosphoric acids; stimulates blood formation, enhances the growth and development of bone tissue, improves the function of the nervous system.

Glutamic acid is involved in metabolic processes, contributes to the neutralization and release of ammonia, stimulates the transmission of excitation in the synapses of the central nervous system.

Methionine is an essential amino acid, is necessary for growth and nitrogen balance of the body, takes part in the processes of peremetilirovaniya and transsulfurization, prevents fatty infiltration of liver cells.

Vitamins and trace elements are in the preparation in physiological, balanced doses that meet the needs of the human body.

Pharmacokinetics of the drug has not been studied.

Indications for use.

The drug is shown as a preventive and therapeutic agent:

with mental and physical stress;

hypovitaminosis, increased body’s need for vitamins and trace elements due to unbalanced nutrition, adherence to a special diet, gastrointestinal disorders;

during the period of recovery after serious illnesses, operations, injuries and stressful states;

to increase the overall resistance of the body and the prevention of infectious diseases during epidemics (such as, for example, influenza);

Glutamic acid for children

to stimulate the healing of wounds, burns;

in order to reduce toxicity and reduce side effects in antibiotic treatment, during and after chemotherapy;

in the complex treatment of atherosclerosis, disorders of cerebral circulation and cardiovascular insufficiency.

Increased sensitivity to the drug, severe renal dysfunction, gout, hyperuricemia, nephrolithiasis, erythremia, erythrocytosis, thromboembolism, active form of tuberculosis, fructose intolerance, thrombophlebitis, hypervitaminosis A and E, a disturbance of iron metabolism or copper, thyrotoxicosis, chronic glomerulonephritis, chronic heart failure, history of sarcoidosis, active peptic ulcer of the stomach and duodenum.

Appropriate security measures when applying.

When using the drug must comply with the dosage and duration of the course of administration.

In the absence of a therapeutic effect or the occurrence of adverse reactions should consult a doctor for advice on the further use of the drug.

The color of urine in yellow color is possible, which is a completely safe symptom and is explained by the presence of riboflavin in the preparation.

Glutamic acid for children

The drug is prescribed with caution in severe lesions of the liver, gastric ulcer and duodenal ulcer, patients with nephritis, chronic pancreatitis, gallstone disease, decompensation of cardiac activity, coronary heart disease, diabetes mellitus, patients with neoplasms (except for cases involving megaloblastic anemia)) urolithiasis.

When prescribing Kadevita ®, as well as other multivitamin preparations, a full-fledged protein diet is necessary, contributing to the better absorption and metabolism of vitamins, especially water-soluble ones.

Kadevit ® is not recommended to be prescribed together with other vitamins and preparations containing trace elements, because of the possible overdose of the latter.

Use during pregnancy or lactation.

During pregnancy or breastfeeding, the drug is taken only on the recommendation of a doctor. The dose of vitamin A should not exceed 5,000 IU for pregnant women and women planning a pregnancy.

Large doses of retinol (over 10,000 IU) should not be taken during breastfeeding because of the risk of hypervitaminosis A in infants.

The ability to influence the reaction rate when driving or working with other mechanisms. There is no data on the effect of the drug on the ability to drive a car or work with complex mechanisms.

Children. This dosage form is not intended for use in children under the age of 14 years.

Dosage and administration.

The drug is taken orally after a meal.

With the preventive purpose, Kvadevit ® is prescribed for adults and children over 14 years old, 1 tablet per day, for older people – 1 tablet 2 times a day. The duration of the prophylactic course is 1-2 months.

For the purpose of treatment, apply 1 tablet 3 times a day. The course of treatment is 3-4 weeks. Repeated courses are held after a 3-month break.

During pregnancy and lactation, the drug is used solely as prescribed by a doctor. In the first trimester – no more than 1 tablet per day, in the second and third trimester – no more than 2 tablets per day. In the period of breastfeeding with a preventive purpose, take 1 pill per day, with medical treatment – 1 pill 2 times a day.

No cases of drug overdose Kvadevit ® were reported.

Overdose may cause allergic reactions (itching, skin flushing, skin rashes) and dyspeptic symptoms (nausea, vomiting, diarrhea, epigastric pain), changes in the skin and hair, abnormal liver function, headache, drowsiness, lethargy, flushing of the face irritability.

Treatment: drug withdrawal, symptomatic therapy.

In the recommended doses, the drug is well tolerated and rarely causes side effects, which, as a rule, are associated with the individual intolerance of one of the components of the drug.

On the part of the immune system: allergic reactions are possible in individuals with hypersensitivity, including anaphylactic shock, angioedema, hyperthermia; bronchospasm in persons with hypersensitivity to vitamins A, C, group B.

From the skin and subcutaneous tissue: rash, hives, itching, redness of the skin.

On the part of the digestive tract: dyspepsia, nausea, vomiting, diarrhea, epigastric pain, belching, constipation, an increase in the secretion of gastric juice.

From the nervous system: headache, dizziness, irritability, drowsiness.

Others: it is possible to color urine yellow, sweating, blurred vision.

With long-term use of the drug in high doses, it is possible: irritation of the mucous membrane of the digestive tract, arrhythmias, paresthesia, hyperuricemia, transient increase in AST activity, lactate dehydrogenase, alkaline phosphatase, reduced glucose tolerance, hyperglycemia, impaired kidney function, dryness and cracks in the palms and feet, dryness and cracks in the palms and the feet. hair loss, seborrheic rashes.

Interaction with other drugs and other types of interactions.

The drug is not recommended to take simultaneously with other multivitamins, since it is possible overdose of the latter in the body.

Vitamins A and E mutually reinforce the action and are synergists. Retinol reduces the anti-inflammatory effect of glucocorticoids. Can not be taken at the same time with nitrites and cholestyramine, since they violate the absorption of retinol.

Vitamin A should not be administered with retinoids, since their combination is toxic.

Preparations containing iron inhibit the action of vitamin E. Vitamin E cannot be used together with preparations of iron, silver, or agents with an alkaline medium (sodium bicarbonate, trisamine and

Vitamin C enhances the effect of sulfonamides (risk of crystalluria), penicillin, increases iron absorption, reduces the effectiveness of heparin and indirect anticoagulants. Vitamin C absorption decreases with simultaneous use with oral contraceptives.

Vitamin B6 weakens the effect of levodopa, protects or reduces the toxic effects that are observed with the use of isoniazid and other anti-TB drugs.

Thiamine, affecting the processes of polarization in the field of neuromuscular synapses, can weaken the curare-like action.

PASK, cimetidine, calcium preparations, alcohol reduce the absorption of vitamin B12.

Folic acid reduces plasma concentrations of phenytoin, with other antiepileptic drugs possible mutual reduction of clinical efficacy.

Riboflavin is incompatible with streptomycin and reduces the effectiveness of antibacterial drugs (oxytetracycline, doxycycline, erythromycin, tetracycline, and lincomycin).

Tricyclic antidepressants, imipramine and amitriptyline inhibit riboflavin metabolism, especially in heart tissues.

Shelf life. 2 years.

Storage conditions. Store in original packaging at a temperature not higher than 25 ºС.

Keep out of the reach of children.

Packaging. 10 tablets in a blister; 3 blisters in a pack.

Vacation category. Over the counter.

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