Cough plaster for kids

In this article, you can read the instructions for use of the drug. Olfen. Presented reviews of visitors to the site – the consumers of this medicine, as well as the opinions of medical experts on the use of Olfen in their practice. A big request to add your feedback on the drug more actively: the medicine helped or did not help to get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogs Olfen in the presence of available structural analogues. Use for the treatment of pain and inflammation in rheumatoid and articular diseases and syndromes in adults, children, as well as during pregnancy and lactation.

Olfen – analgesic and anti-inflammatory drug from the group of nonsteroidal anti-inflammatory drugs (NSAIDs). The drug contains the active ingredient diclofenac sodium, which inhibits the enzyme cyclooxygenase. Due to the inhibition of cyclooxygenase activity, the synthesis of prostaglandins from arachidonic acid is reduced. Reducing the number of prostaglandins in the affected tissues leads to a decrease in the intensity of the inflammatory process. The analgesic effect of the drug is due to a decrease in the level of prostaglandins in the tissues of the central and peripheral nervous system, as a result of which the susceptibility of nerve cells to stimuli is reduced, generation is prevented and the conduction of pain impulses along nerve structures is slowed down. In addition, the drug has antipyretic effects, due to the direct effect of diclofenac on the thermoregulation center in the hypothalamus. The drug effectively eliminates morning stiffness, improves joint mobility and relieves pain in patients suffering from diseases of the musculoskeletal system.

Composition

Cough plaster for kids

Diclofenac sodium + excipients.

Diclofenac sodium + lidocaine hydrochloride + excipients (shots in vials for injection Olfen).

Pharmacokinetics

The drug is well absorbed into the systemic circulation through oral and rectal administration. The peak concentration of the active substance in the blood plasma is noted after 0.5-3 hours, depending on the form of release. For the drug is characterized by a high degree of communication with plasma proteins. It is metabolized in the liver, excreted mainly by the kidneys, both unchanged and in the form of metabolites. A minor part of the drug is excreted by the liver.

When using the drug in the form of prolonged capsules, therapeutically significant plasma concentrations of the drug are maintained for a longer time than when using other forms of the drug.

Indications

The drug is used to relieve pain in degenerative-inflammatory diseases of the musculoskeletal system and soft tissues, including arthritis, arthrosis, rheumatoid arthritis, tendovaginitis, bursitis, lumbago, sciatica, gouty arthritis.

The drug can be prescribed to relieve pain and reduce tissue swelling in patients undergoing surgery.

The drug is used as an analgesic for primary dysmenorrhea, migraine, renal and hepatic colic.

Olfen may be prescribed in the complex treatment of acute infectious diseases of upper respiratory tract.

Forms of release

Tablets, coated 50 mg Olfen Laktab.

Capsules of the prolonged action of 100 mg Olfen SR Deprokaps.

Solution for injection 75 mg (shots in ampoules for injection).

Rectal Capsules Olfen Rectocaps 100 mg (sometimes mistakenly called rectal suppositories).

There were no other dosage forms, be it a gel, ointment or cream, at the time of publication of the drug card in the Reference Book.

Instructions for use and dosage

Tablets Olfen 50 Laktab

The drug is intended for oral administration. The tablet should be swallowed whole, not chewed and not crushed, drinking plenty of water. The drug is recommended to take before meals. The duration of treatment is determined by the attending physician individually for each patient.

Adults are usually prescribed 1 tablet of the drug 1-3 times a day.

The maximum daily dose of the drug is 150 mg.

Adults with primary dysmenorrhea are usually prescribed 1 tablet of the drug 1-3 times a day. If necessary, the dose can be increased to 1 tablet of the drug 4 times a day. The drug in a dose of 200 mg / day is allowed for primary dysmenorrhea for no more than 4 consecutive cycles.

With prolonged therapy with the drug should not exceed the daily dose of 100 mg of diclofenac.

Extended Capsules Olphen deprocaps

The drug is intended for oral administration. The capsule is recommended to be swallowed whole, without chewing or grinding, washing it down with plenty of water. To reduce the risk of side effects should take the drug before meals. The duration of treatment is determined by the attending physician individually for each patient.

Adults are usually prescribed 1 capsule of the drug 1 time per day.

The maximum daily dose of the drug is 1 capsule.

Adults with primary dysmenorrhea are usually prescribed 1 capsule of the drug 1 time per day. If necessary, the dose can be increased to 1 capsule of the drug 2 times a day. The drug in a dose of 200 mg / day is allowed for primary dysmenorrhea for no more than 4 consecutive cycles.

Rectal Capsules Olfen Rectocaps

The drug is intended for rectal use. The capsule should not be divided or crushed. Before use, the capsule may be moistened with water for more convenient administration. The capsule is injected with a blunt end, after the use of the drug, the patient should take a horizontal position and not rise for at least 20 minutes. The duration of the course of treatment and the dose of the drug is determined by the attending physician individually for each patient.

Adults are usually prescribed 1 capsule or suppository of the drug 1 time per day.

Injection

The drug is intended for parenteral (intramuscular) administration. Only intramuscular administration of the drug is allowed. The solution is injected deep inside the muscle, usually the injection is carried out in the upper outer quadrant of the gluteus muscle. With repeated administration of the drug, the left and right gluteal muscle should be alternated. The duration of the course of treatment and the dose of the drug is determined by the attending physician individually for each patient.

Adults are usually prescribed 1 ampoule of the drug 1 time per day.

With acute pain syndrome (for example, with hepatic colic), it is possible to administer the drug 2 times a day with an interval of 2-3 hours.

The maximum duration of use of the drug in the form of a solution for injection 2 days. If it is necessary to continue drug therapy, the parenteral form of the drug should be replaced by oral or rectal.

It is allowed to combine the dosage forms of the drug, but it should be considered the total daily dose of diclofenac, which should not exceed 150 mg.

Patients receiving long-term therapy with Olfen should regularly monitor liver, heart and kidney function, as well as the blood picture.

The plaster Olfen must be pasted on the affected area 1-2 times a day. The skin where the product is used must be clean and dry. Do not pre-lubricate it with cream.

You need to apply a plaster without stretching it. When used in the field of mobile joints, for example, on the elbows, it is desirable to strengthen it with a mesh bandage.

Before hygiene procedures, the plaster can be removed and then pasted again.

Side effect

  • nausea, vomiting;
  • violation of the chair;
  • abdominal pain, including spastic character;
  • flatulence;
  • digestive disorders;
  • anorexia;
  • stomatitis;
  • pancreatitis;
  • gastrointestinal bleeding;
  • ulcerative colitis;
  • hemorrhagic colitis;
  • hepatitis;
  • jaundice;
  • headache;
  • dizziness;
  • cerebral circulatory disorders;
  • fatigue;
  • impaired memory and orientation in space;
  • violation of sleep and wakefulness;
  • paresthesias;
  • convulsions;
  • emotional lability;
  • aseptic meningitis;
  • impaired vision and hearing;
  • noise in ears;
  • change in taste;
  • swelling;
  • renal failure;
  • the presence of blood in the urine;
  • interstitial nephritis;
  • necrotizing papillitis;
  • nephrotic syndrome;
  • heart rhythm disorder;
  • cardialgia;
  • high blood pressure;
  • heart failure;
  • thrombocytopenia, leukopenia, anemia, agranulocytosis;
  • skin rash;
  • itching;
  • hives;
  • Stevens-Johnson syndrome;
  • Lyell’s syndrome;
  • eczema;
  • alopecia;
  • photosensitivity;
  • anaphylactic shock;
  • angioedema;
  • pneumonia;
  • vasculitis;
  • exacerbation of hemorrhoids;
  • with intramuscular administration of the drug may develop necrosis and abscess at the injection site.

Contraindications

  • individual sensitivity to the components of the drug and other drugs of the group of nonsteroidal anti-inflammatory drugs, including a history of aspirin triad;
  • peptic ulcer of the stomach and duodenum;
  • ulcerative colitis;
  • acute hemorrhoids;
  • severe heart failure;
  • patients with severely impaired liver and kidney function (creatinine clearance less than 30 ml / min);
  • patients who have a tendency to bleed, including patients at risk of developing postoperative bleeding and patients with impaired homeostasis and hematopoiesis;
  • patients receiving high-dose anticoagulant therapy and non-narcotic pain medications;
  • pregnant women in the 3rd trimester of pregnancy;
  • children under the age of 14 (due to the lack of reliable data on the safety of the use of the drug in this age group);
  • proctitis and other diseases of the rectum (rectal capsules).

Use during pregnancy and lactation

Olfen can be prescribed in the 1st and 2nd trimesters of pregnancy by the attending physician, if the expected benefit to the mother is higher than the potential risks to the fetus. During pregnancy, the drug should be used in the minimum effective doses and for as short a period as possible. Use of the drug is contraindicated in the 3rd trimester of pregnancy.

If necessary, the use of the drug during lactation is recommended to consult with your doctor and decide on the interruption of breastfeeding.

Cough plaster for kids

Use in children

Contraindicated in children under 14 years of age (due to the lack of reliable data on the safety of the drug in this age group).

special instructions

It is used with caution in patients with porphyria, impaired renal function, dehydration, impaired blood clotting, heart disease, including heart failure.

With long-term treatment, it is necessary to periodically study the blood count and liver function, analysis of fecal occult blood.

It should not be applied to damaged or exposed skin, in combination with an occlusive dressing; Do not allow contact with eyes and mucous membranes.

Influence on ability to drive motor transport and control mechanisms

Because of the possible reduction in the reaction rate, driving a motor vehicle and working with machinery is not recommended.

Drug interaction

The drug with combined use increases plasma concentrations of lithium and digoxin.

Diclofenac sodium reduces the effectiveness of diuretics and increases the risk of hyperkalemia in combination with potassium-sparing diuretics.

When using the drug simultaneously with other drugs of the group of non-narcotic pain medications, NSAIDs, as well as with glucocorticosteroids (GCS), the risk of side effects increases.

If necessary, the simultaneous use of the drug with anticoagulants should be regularly monitored prothrombin time.

The simultaneous use of alcohol and the drug Olfen is forbidden – the risk of gastrointestinal bleeding is high.

The drug has virtually no effect on the effectiveness of hypoglycemic agents, however, there is evidence of the development of hypoglycemia and hyperglycemia in patients who took diclofenac sodium together with hypoglycemic agents.

The drug in the combined use enhances the nephrotoxicity of cyclosporine and the toxic effect of methotrexate, you should observe the interval of at least a day between taking diclofenac and methotrexate.

With the combined use of the drug with quinolone may develop seizures.

Analogues of the drug Olfen

Structural analogues of the active substance:

  • Artrex;
  • Veral;
  • Voltaren;
  • Voltaren Emulgel;
  • Diklak;
  • Diklak Lipogel;
  • Diklo F;
  • Diklobene;
  • Dikloberl;
  • Diklovit;
  • Diclogene;
  • Diclomax;
  • Diclomelane;
  • Diklonak;
  • Diclonat P;
  • Dicloran;
  • Diclorium;
  • Diclofen;
  • Diclofenac;
  • Diclofenac Potassium;
  • Diclofenac Sodium;
  • Diclofenac retard;
  • Diclofenaclong;
  • Diclofenacol;
  • Diphen;
  • Dorosan;
  • Naklof;
  • Naklofen;
  • Naklofen Duo;
  • Olfen Depokaps;
  • Olfen Rectocaps;
  • Ortofen;
  • Orthofer;
  • Orthoflex;
  • Rapten Duo;
  • Rapten Rapid;
  • Revmavek;
  • Revodina retard;
  • Remetan;
  • Sanfinak;
  • SwissJet;
  • TabukDi;
  • Feloran;
  • Feloran Retard;
  • Flotak.
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