The use of the drug "Omez DSR" is important for those who suffer from stomach problems. The tool is designed specifically to combat ulcers, and it also inhibits the production of gastric juice. The complex effect exerted by the active substances of the drug, allows to obtain good results in the treatment of gastric ulcers, duodenal ulcers.
The best for your health
Often patients, having received a prescription for the drug in question, think about the difference between Omez and Omez DSM? The price of these medicines is different. Why does the doctor write out the second option?
The explanation is simple: "Omez" contains only one active substance that is effective in ulcers, but "Omez JEM" has an additional component that makes the therapy better, more effective. In addition, the tolerance of Omez JEM is higher, that is, the treatment is accompanied by fewer unpleasant side effects.
Treat – do not cripple
As follows from the instructions for use, "Omez DSR", this tool has a good effect not only in the treatment of gastrointestinal ulcers, but also in Zollinger-Ellison’s disease. The duration of therapy is usually short-term, the first improvements in the patient’s condition are noticed already after 4-5 days from the start of the course.
The instructions for Omez JEM calls for the use of the drug with extreme caution. During clinical trials it was revealed that in case of renal failure, the probability of quite severe side effects is high. If the doctor makes a decision on this diagnosis to conduct therapy with Omez DSR, it is necessary to regularly monitor the patient’s condition. Also, when developing a treatment strategy, it is important to remember a number of contraindications. All of them are listed in the instructions "Omez JEM".
How to treat?
What is included in the composition of the drug (and in fact it is in the composition of the difference between "Omez DSR" and "Omez D", except, of course, prices), which explains its fast, pronounced effect? Main active ingredients:
In one capsule, omeprazole is present in an amount of 20 mg, domperidone – 30 mg. There are also additional components that improve the process of assimilation of the drug, simplify patient’s use of it and enhance the effect of active substances. Among the additional components in each capsule are sucrose, lactose and mannitol, as well as talc and titanium dioxide. There are many other compounds. The full composition can be found if you read the instructions for use "Omez JEM".
When to take?
All indications and contraindications of the drug "Omez JEM" can be found in the accompanying instructions. This liner is necessarily present in the package containing the drug. In addition, the doctor, when prescribing this remedy, also introduces the patient both to the reason why this treatment option was chosen for him, and to the dangerous factors that provoke negative effects when taking the medicine.
As a rule, “Omez DSR” is resorted to if an acid-dependent, incontinent health disorder complicated by nausea is diagnosed. Also "Omez DSR" is indispensable for therapy (complicated vomiting):
- gastroesophageal reflux disease.
And when it is impossible?
About contraindications in detail tells the instructions for use "Omez JEM". You can not resort to therapy, if it is known that the patient’s body is hypersensitive to one or more substances that make up the drug.
Particularly noteworthy is the fact that the use of "Omez JEM" can not be at high susceptibility to substituted benzimidazoles.
Instructions for use of the drug "Omez DSM" contains restrictions for women: therapy is prohibited during the period of gestation and breastfeeding of the child. Also, the medication is not intended for children, it can only be used from 12 years.
Omez JEM: compatibility with drugs and diseases
The main component of the drug, omeprazole, belongs to the IPP group (“proton pump inhibitors” means). All compounds with similar properties may not be used in combination with nelfinavir. In addition, a strict ban is imposed on the use of "Omez JEM" (reviews confirm this) while taking medications that affect the length of the QT interval in a big way. Also, the risk to health is the use of "Omez DSM" (instructions for use draws attention to this) and CYP3A4 inhibitors.
A number of diseases also impose restrictions on the possibility of drug treatment with Omez JEM. The manufacturer prohibits the use of the drug for:
- incorrect, insufficient functioning of the liver, kidneys;
- increased duration of periods of conduction of the heart muscle, QT;
- electrolyte imbalance;
Restrictions on use: the list goes on
Instructions for use, reviews of "Omez JEM" note that the tool can not be used if the patient’s condition suggests a suspicion of increased risk of stimulating the ventricle to the left. A dangerous situation develops when bleeding in the digestive tract, perforation. With increased danger associated mechanical obstruction.
In parallel with the drug "Omez DSR" (readings fade into the background) you can not use CYP3A4 inhibitors, which have a pronounced, strong effect. In particular, simultaneous treatment with the described agent and ketoconazole, erythromycin is not allowed. If the patient is already undergoing therapy with any CYP3A4 inhibitor, it is necessary to notify the attending physician. As a rule, they are looking for an alternative to Omez JEM. Notice how Omez differs from Omez JEM: in the second agent domperidone is present in the composition, but both of them are unacceptable for therapy in case of using CYP3A4 inhibitors.
Compatibility with other drugs: know the enemy by name
For health, an increased risk is borne by the simultaneous use of the medication in question and agents that affect the duration of QT. This means that it is impossible simultaneously with Omez JEM to be treated with drugs containing:
In addition to these medicines, the ban on the use of "Omez JEM" imposes the use of drugs Ritonavir, Telaprevir. There may be other names incompatible with the substance being described; therefore, it is necessary to introduce a physician into a course of therapy that a person is already undergoing, paying particular attention to medications that affect the cardiovascular system. It is worth remembering that quite often new drugs appear on the market, and only a professional doctor knows the parameters of their compatibility with the Omez JEM under review.
How to use?
The scheme is usually chosen by the attending physician with an eye on the instructions for use of Omez JEM. In the classic version of therapy involves the use of one capsule in the morning. The manufacturer recommends drinking the medicine an hour before taking the meal. The tool must be used in the version as it is released. The capsule is not chewed, does not break, do not dissolve – it is necessary to swallow completely.
The digestibility of the active component of the drug depends on it.
In the day in the body should receive no more than 30 mg of domperidone. Therefore, the maximum dose of the drug for 24 hours is one capsule. The duration of such therapy is determined by the doctor, focusing on the tolerability of the drug and the presence of symptoms of an ulcer. The manufacturer regulates only the upper limit of the possible duration of regular use of the drug: 7 days.
Body oversupply: how is it expressed?
- heart rhythm disorder;
- loss of vision;
- unclear, embarrassed, lost condition;
- activation of sweat glands;
- gag reflex;
Visually notice that a person suffers from an excess of omeprazole, it is possible on the red face – blood rushes to the skin. The patient himself feels that his mouth is dry, apathetic, depressive. As a rule, patients complain of diarrhea.
Surplus of domperidone: what is expressed?
If too much domperidone has accumulated in the body when taking Omeza JEM, it manifests itself with the following negative phenomena:
- disturbed heart rhythm;
- problems with orientation in space;
- pressure increases;
- consciousness is disturbed;
- tends to sleep;
- man is overly excited.
Overdose: what to do?
At the present time, a specific antidote was not found. When overdosing is detected, it is necessary to assess the patient’s condition, eliminate the most dangerous symptoms for life and health, and continue therapy by selecting medications that improve the patient’s sense of self.
Practice has shown that hemodialysis does not give a positive result. This is due to the increased level of binding to plasma proteins of the active components of the drug. Therefore, it is impossible to remove the surplus of "Omez DSR" by this method.
It is known that portability is high, as indicated in the instructions for Omez JEM preparation (there are analogues of this medication on sale, they will be listed below, but the real need for them really rarely occurs). All side effects that are known to physicians are reversible, classified as weak, and therefore cannot serve as a reason to stop treatment.
If a patient takes omeprazole for too long, the body may react in a certain way. May occur:
- stomach ache;
- problems with the chair;
- increased gas formation;
- dry mouth;
- inflammation of the oral mucosa;
- disturbance in the taste buds;
- problems with appetite;
What else is possible?
When omeprazole is in excess in the body, the liver can react to this, a system of organs excreting bile. It is expressed by hepatitis. If metabolism turned out to be the weakest side, too much omeprazole concentration manifests itself as a deficiency of sodium, magnesium, and calcium.
The central nervous system, PNS, for too long a course of use of Omez JEM respond:
- depressive conditions;
- hallucinations are seen;
- consciousness is confused.
More often, such side effects are observed if the patient is seriously ill.
In some cases, with the passage of therapy against the background of a high concentration of omeprazole in the body, people become aggressive, overly excited. Others complain of tinnitus, possibly a state of vertigo.
Musculoskeletal and skin: side effects
Incorrect use of Omez JEM, too long a course of reception, the accumulation of the active component in the body can lead to failures in the operation of these systems. Patients complain about:
- muscle weakness;
- Stevens Johnson syndrome;
- hair loss;
- increased sensitivity to light;
- itchy, covered with rash skin.
There are cases of anaphylactic shock, angioedema.
Unpleasant phenomena: what else to be ready for?
When studying samples of patients’ liquids (in the laboratory) suffering from side effects while taking Omez JEM, non-standard parameters are detected. The levels of agranulocytosis, pancyto, platelet, and leukopenia change.
The concentration of liver enzymes is increasing. This is characteristic of those who, before taking the Omez JEM course, were seriously ill with ailments affecting the liver. In some cases, signs of encephalopathy and hepatitis are recorded. Occasionally, patients experience manifestations of insufficient functioning of the liver.
The endocrine system may respond to the intake of the drug under consideration by gynecomastia. Immunity in rare cases shows increased sensitivity. Patients undergoing treatment often complain of indisposition, a feeling of weakness without any specification. Rarely, but recorded cases of jade, bronchial spasms, feverish condition. The activity of the sweat glands may be activated, edemas occur. Lost visual acuity. The disorder is restored when the concentration of omeprazole in the body tissues is normalized.
Domperidone: Specificity of Adverse Reactions
This active component of Omeza JEM has its own list of side effects, somewhat different from the above. Patients are faced with gastrointestinal problems, including changes in taste, heartburn and upset stool. The nervous system reacts with lethargy, irritability, sleep disturbances, apathetic states, or, conversely, excessive irritability.
A surplus of domperidone may manifest itself as galactorrhea, problems with the menstrual cycle and excess of the amount of prolactin. A prolongation of the QT interval, a change in the rhythm and frequency of heart contractions is likely. In rare cases, cardiac death was diagnosed. In comparison with the originally developed composition of the drug, the amount of domperidone per capsule was reduced to reduce the likelihood of adverse reactions from the cardiovascular system.
Domperidone: what other troubles are possible?
In some cases, the immune system reacts negatively to domperidone. This is manifested by allergic reactions. Perhaps the occurrence of a depressing effect psyche, manifested by depressive states, an increased level of anxiety. Patients become nervous, lose their libido partially or completely.
In a number of cases, convulsions were recorded, a constant desire to sleep, a general sluggish state. For some, the skin was covered with a rash, itching appeared. There is the likelihood of urticaria. In women, they can increase in size (slightly), the mammary glands become more sensitive, discharge and swelling are possible.
A number of patients were diagnosed with pain in the legs, dysuria, increased or delayed urination. Perhaps the development of infectious inflammation of the oral mucosa, eyes. In some cases, the concentration of cholesterol in the blood rises, the tests reflect abnormal liver function values. The concentration of prolactin increases in the blood. The frequency of occurrence of any of these side effects – 7% and below. Almost all cases are easily tolerated, symptoms disappear in a short time. The most serious unpleasant effects of taking the medication disappear when the course of treatment ends or the dose is reduced.
What can be replaced?
If for any reason it is not possible to use the described remedy, in consultation with your doctor, you can replace it with a drug with a similar effect. Known analogues "Omeza JEM":
The choice in favor of an alternative medication remains with the attending doctor. Independent correction of both the course of treatment and the single dose is not allowed, as indicated by the manufacturer in the instructions for use of the medication. You must understand that self-treatment is dangerous to health and even life. The cost of one package of Omez DSR in prices for the current year is about 400 rubles.