Generic Name: desvenlafaxine (Oral route)
Des vein la fax een
Oral (tablet, extended release)
Antidepressants increase the risk of suicidal thoughts and behavior in children, adolescents and young people with major depressive disorder (MDD) and other mental disorders in short-term studies. Short-term studies did not indicate an increased risk of suicidality with antidepressants compared with placebo in adults over 24, and there was a decrease in risk with antidepressants compared with placebo in adults 65 years of age and older. This danger must be balanced with clinical needs. Patients closely monitor clinical deterioration, suicidality or unusual changes in behavior. Families and caregivers should be notified of the need for close observation and communication with the legislator. Not approved for use in pediatric patients.
Frequently used brand name (s)
Available dosage forms:
- Tablet, extended release
Therapeutic Class: Antidepressant
Pharmacologic Class: Serotonin / Norepinephrine Reuptake Inhibitor
Uses for Pristiq
Desvenlafaxine is used to treat depression.
Desvenlafaxine belongs to a group of drugs known as selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is believed that these drugs work by increasing the activity of chemicals called serotonin and norepinephrine in the brain.
This medicine is available only with your doctor.
Before using Pristiq
Having decided to use the medicine, the risks of taking the medicine must be evaluated with the good it will do. This is a decision that will make you and your doctor. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you need any other types of allergies, such as food, dyes, preservatives, or animals. For non-prescription products, carefully read the sticker or package of ingredients.
Appropriate studies have not been performed on the relationship of age to the effects of desvenlafaxine in the pediatric population. Safety and efficacy has not been established.
Relevant studies have not yet demonstrated geriatric-specific problems that limit the usefulness of desvenlafaxine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require an adjustment in dose or additional attention in these patients.
Animal studies have shown negative effects and there are no adequate studies of pregnant women or no animal studies have been conducted and there are no adequate studies in pregnant women.
There are no adequate studies by women to determine the infant risk when using this medication during breastfeeding. Weigh the potential benefits of the potential risks before taking this drug while breastfeeding.
Although some medicines should not be used together at all, in other cases two different medicines can be used together even with the possibility of interaction. In these cases, your doctor may need to change the dose, or other precautions may be required. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions were selected based on their potential value and are not necessarily all inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some medications you are taking.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. With both medicines set together, your doctor may change the dose or how often you use one or both of the medicines.
- Antithrombin III person
- Dermatan sulfate
- Pentosan Polysulfate Sodium
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. With both medicines set together, your doctor may change the dose or how often you use one or both of the medicines.
- Flufenamic acid
- Mefenamic acid
- Niflumic acid
- Tiaprofenic acid
Interaction with food / tobacco / alcohol
Some medicines should not be used at or around the time of eating food or eating certain types of food with interactions may occur. The use of alcohol and tobacco with some medicines may also cause interactions to occur. The following interactions were selected based on their potential value and are not necessarily all inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine or give you special instructions regarding the use of food, alcohol or tobacco.
Other health problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Bipolar disorder (mental illness with cycles of elation and depression) or
- Bleeding problems or
- High blood pressure, uncontrolled or
- Hypercholesterolemia (high cholesterol in the blood) or
- Narrow angle of glaucoma (increase in pressure inside the eye) or
- Capture (convulsions), history. can make these conditions worse.
- Heart attack, recent or
- Heart disease or
- The move, the story. use with caution. May lead to an increase in heart rate and blood pressure.
- Kidney disease or
- Liver disease, you may need a lower dose of this medicine. Talk with your doctor if you have problems.
Proper Use of Pristiq
Take this medicine only as directed by your doctor for the benefit of your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
Desvenlafaxine may be taken with or without food and must be taken at the same time each day.
Swallow extended-release tablet whole with water. Do not dissolve, crush, break, or chew it.
This medicine should come with a medication guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
The dose of this medicine will be different for different patients. Follow your doctor’s orders or instructions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it if your doctor tells you to do this.
The medicine you are taking is determined on the basis of medicine. In addition, the number of doses you take each day, the time between doses and the length of time you take medicine depends on the medical problem for which you use the medicine.
- For mental depression:
- For oral dosage form (extended-release tablets):
- Adults. 50 milligrams (mg) once a day. Your doctor may adjust your dose as needed.
- Children. dose and use should be determined by your doctor.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your dosing schedule. Do not double dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine and medicine is no longer needed.
Ask your healthcare professional how to free up any medicine you do not use.
Precautions when using Pristiq
It is important that your doctor check your progress through regular visits, to allow changes in your dose and help reduce any side effects. Blood tests may be needed to check for unwanted effects, such as increasing cholesterol and fat in the blood.
Desvenlafaxine may cause some people to be agitated, irritable, or display other abnormal behavior. This may also cause some people have suicidal thoughts and tendencies or become more depressed. If you, your child, or your caregiver have any of these side effects, tell your doctor or doctor your child immediately.
Do not stop taking this medicine without first checking with your doctor. Your doctor may want to gradually reduce the amount you are taking before stopping it to completely reduce the chance of side effects.
Do not be desvenlafaxine for 2 weeks (14 days) to take a monoamine oxidase (MAO) inhibitor (for example, isocarboxazid [Marplan?], Phenelzine [Nardil?], Selegiline [Eldepryl?] Or tranylcypromine [Parnate?]). Do not take MAO inhibitor within 7 days after taking desvenlafaxine. Talk to your doctor about this if you have questions.
Make sure your doctor knows about all the other medicines you use. Desvenlafaxine can cause a serious condition called serotonin syndrome or neuroleptic malignant syndrome (NMS) —as a reaction when treated alone or with certain medicines, such as linezolid [for example, Zyvox?], Lithium, tryptophan, St. John’s wort, or some pain and migraine medications (for example, tramadol [Ultram?], Sumatriptan [Imitrex?], zolmitriptan [Zomig?] or rizatriptan [Maxalt?]). Talk with your doctor if you are concerned about this and check with your doctor first before taking other medicines.
Do not use alcohol while you are taking desvenlafaxine.
Contact your doctor right away if you develop any allergic reactions to this medicine, such as rash, hives, swelling or difficult to breathe.
This medicine may cause serious lung problems (eg, interstitial lung disease, eosinophilic pneumonia). Check with your doctor right away and stop using this medicine if you have chest discomfort or tightness, coughing, difficulty or difficulty breathing, difficulty breathing, or shortness of breath.
Make sure your doctor knows if you are also using aspirin, an NSAID (for example, ibuprofen, naproxen, Advil. Aleve. Celebrex. Or Motrin?) Or blood thinner (for example, warfarin [Coumadin?]). Desvenlafaxine may increase your risk of bleeding problems, especially when taken with these medicines.
You may need to have your blood pressure and pulse pressure checked before and when using this medicine. If you notice any changes in your blood pressure and pulse, call your doctor right away. If you have questions about this, talk to your doctor.
Hyponatremia (low sodium in the blood) may occur while using this medicine. Check with your doctor right away if you have a headache; difficulty concentrating; memory changes; confusion; or weakness and instability on your feet. Symptoms of severe hyponatremia include: seeing, hearing, or feeling that does not exist; fainting; or seizures.
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything that could be dangerous if you are not alert.
Pristiq side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur, they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- fast, pounding, or irregular heartbeat or pulsed
- numbness or tingling in the arms or legs
- perspiration in arms, arms, hands or legs
- shaking or shaking hands or feet
- problems thinking, talking or walking
Number not known
- Actions that are out of control
- stretched, extended or more pupils (black part of the eye)
- blood in the stool
- blood in the urine
- chest tightness
- convulsions (seizures)
- joint pain, stiffness or swelling
- large, bush like a tumor on the face, eyelids, lips, tongue, throat, hands, feet, legs or genitals
- Loss of bladder control
- muscle cramps or jerking of all limbs
- nose over the edge
- skin redness
- Sudden loss of consciousness
- swelling of the eyelids, face, lips, hands or feet
- say feelings and actions with excitement
- restless breathing or swallowing
- unusual bruising
- vomiting blood
Get emergency help right away if any of the following symptoms of an overdose occur:
- Abdominal or stomach pain
- abdominal distension or stomach swelling
- blurred vision
- burning, crawling, itching, numbness, prickling. pins and needles? or tingling feelings
- chest pain or discomfort
- dark colored urine
- difficulty having a bowel movement (stool)
- dry mouth
- feeling of constant movement of self defense or surroundings
- Increased sweating
- light stools
- muscle cramps, pain or stiffness
- overactive reflexes
- poor coordination
- feeling spinning
- slow pulse
- unusual tiredness or weakness
- yellow eyes and skin
Some side effects may occur that usually do not need medical attention. These side effects can go away during the treatment process, as your body changes in medicine. In addition, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Reduced appetite
- decreased interest in sexual intercourse
- inability to have or maintain an erection
- more time than normal sperm ejaculation time
- Loss in sexual ability, desire, drive, or performance
- unable to have an orgasm
- drowsiness or unusual drowsiness
- Changes in taste
- change or problems with performing sperm
- Continuing melodies or buzzing or other unexplained tinnitus
- weight loss
- difficult urination
- fear or nervousness
- sensation of heat
- hearing loss
- increase the sensitivity of the eye to light
- lack or loss of strength
- Loss of taste
- can not ejaculate sperm
Other side effects not listed may also occur in some patients. If you notice any other effects, consult your specialist.
Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.
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