Composition and release form
The composition of the medical drug Vazotenz includes the active pharmaceutical substance losartan potassium and minor substances: mannitol, croscarmellose sodium, povidone, magnesium stearic acid, titanium dioxide, steatite.
Vazotenz is made in the form of white rounded white tablets with the designation: 1L – tablets with a dosage of 12.5 mg, 2L – with a dosage of 25 mg, 3L – with a dosage of 50 mg, 4L – with a dosage of 100 mg. The carton box contains 2 blister packs of 7 tablets each.
Pharmacodynamics. This antihypertensive agent Vasotens refers to angiotensin II receptor antagonists. Vazotenz decreases the vascular resistance, the level of epinephrine and aldosterone in the blood, has antihypertensive effect, has a diuretic effect.
The antihypertensive effect of vasotenza appears on the boundary 6 hours after the use of the drug and subsides within 24 hours. The persistent antihypertensive effect of vasotenza appears within 3-6 weeks from the moment of initiation of therapy. Patients with cirrhosis of the liver, require a reduced dosage of the drug Vazotenz,
Pharmacokinetics. The active substance vazotenz losartan means is rapidly excreted from the gastrointestinal tract. The ability to assimilate is 33%. 99% protein binding. The limiting content of losartan in the blood is observed an hour later, the active metabolite 3-4 hours after oral administration.
What do doctors say about hypertension
I have been treating hypertension for many years. According to statistics, in 89% of cases hypertension ends with a heart attack or stroke and death of a person. Approximately two thirds of patients now die within the first 5 years of the disease.
The next fact is that pressure can be knocked down and necessary, but this does not cure the disease itself. The only medicine officially recommended by the Ministry of Health for the treatment of hypertension and used by cardiologists in their work is Normaten. The drug affects the cause of the disease, making it possible to completely get rid of hypertension. Moreover, within the framework of the federal program, every resident of the Russian Federation can receive it for FREE.
Indications for use of the drug Vazotenz
This drug Vazotenz is used to treat:
- Hypertensive disease.
- Chronic heart failure (as an additional drug of general therapy, when ACE inhibitors were not effective enough, or there is intolerance).
Medotherapy Vazotenz is taken orally, regardless of the meal 1 time per day.
Hypertension. Primary dosage of Azotech is 50 mg. In cases where the desired result is not achieved, the dosage can be doubled to 100 mg of the active substance in two applications or once a day.
Heart failure. Primary dosage of Azotech is 12.5 mg. The dosage should be increased in stages over several weeks twice (from 12.5 mg to 25 mg, from 25 mg to 50 mg per day). The maximum dosage per day is not more than 50 mg of the active substance. It is also necessary to take into account the degree of tolerability of the drug Vasozenz by the patient.
Patients taking diuretics in significant doses should observe the dosage of vasotenza. no more than 25 mg per day.
- Individual sensitivity / intolerance to the individual components of Aviation.
- Increased content of potassium in the blood plasma.
- The period of pregnancy and lactation.
- Children under 18 years old.
- Liver insufficiency (with caution).
Use during pregnancy and lactation
Therefore, the use of vazotenza is contraindicated during pregnancy. In cases where it is necessary to treat Vasotensom of a nursing woman, the child should be transferred to artificial feeding for the duration of the course of therapy.
Signs of an overdose of vasotensom can be: lowering blood pressure, tachycardia, bradycardia. The patient is required to provide assistance either through the use of forced diuresis or symptomatic therapy.
Basically, the drug Vazotenz does not have a side effect on the body, it is well tolerated. But in rare cases, there may be negative manifestations: