How to use and what can replace the drug Pyridoxine? Instructions for use, analogues and his testimony will be presented below. You will also learn about the general characteristics of this medication, its contraindications and undesirable reactions.
Components of the drug and its release form
Pyridoxine injections, instructions for use of which are in a pack of paper, go on sale in glass ampoules. The active ingredient of this solution is pyridoxine hydrochloride. Also in the composition of injectable medication is such an additional substance, as water d / and.
We can not say that the drug in question can be purchased in the form of tablets (in banks of 50 pieces).
What is the drug Pyridoxine-Vial? Instructions for use (injections should be prescribed only by a doctor) states that this is a drug that compensates for the deficiency of vitamin B6 in the body.
It is not a secret for anyone that this element is an indispensable participant in all metabolic processes in the human body. It supports and normalizes the activities of the National Assembly.
The phosphorylated form of this drug is a coenzyme of a huge number of enzymes that affect the non-oxidative metabolism of amino acids (including transamination and decarboxylation).
How do Pyridoxine injections work? Instructions for use states that vitamin B6 affects the metabolic processes of cysteine, tryptophan and methionine, as well as glutamine and other amino acids. In addition, it is essential for histamine metabolism and the normalization of fat.
How is pyridoxine hydrochloride distributed in humans? Instructions for use (injections are most often prescribed for intramuscular administration) states that after this substance enters the human body, it is immediately metabolized in the liver. As a result, pharmacologically active derivatives such as pyridoxamine phosphate and pyridoxal phosphate are formed. These components are distributed mainly in muscle tissue, as well as in the nervous system and liver.
Experts note that the drug in question is able to penetrate into the mother’s milk and through the placenta. It is derived through the kidneys and along with the bile.
Indications for administration of the solution
When do patients receive Pyridoxine injections? Instructions for use reports that this tool is actively used for the prevention and treatment of vitamin B6 deficiency in:
- B6-hypovitaminosis, sideroblastic anemia, toxicosis in pregnant women;
- diabetes, leukopenia, dermatitis;
- diseases of the nervous system, herpes zoster, neurodermatitis;
- air and marine disease, exudative diathesis;
- atherosclerosis, psoriasis and other conditions.
Contraindications to the introduction of the solution
In what cases you can not make injections Pyridoxine? Instructions for use does not contain a large list of contraindications. However, it should be noted that it says that this drug is prohibited to use for those patients who show high sensitivity to vitamin B6, as well as its intolerance is observed.
Drug Pyridoxine: instructions for use
Injections, reviews of which we consider a little lower, should be put only after consulting with a specialist.
As a rule, vitamins are recommended to be used in a daily dose of 50-150 mg. It should also be noted that this drug is allowed to be administered not only intramuscularly, but also subcutaneously, intravenously.
The duration of vitamin B6 therapy is determined by the severity of the disease and the type of disorder.
For prophylactic purposes, this agent is prescribed in the amount of 40 mg per day.
How should I take Piridoxine oral medication? Instructions for use (shots and tablets have the same indications) states that this tool is also used to treat hypovitaminosis. Adult patients are prescribed it at a dose of 80 mg four times a day.
Side effects after using the medication
In most cases, the drug Pyridoxine is very well tolerated by patients. In some cases, vitamin B6 can cause allergic reactions, as well as contribute to the hypersecretion of hydrochloric acid.
In medical practice, no cases of overdose with this remedy have been established.
Concurrent use of this drug with cycloserine, isoniazid, and penicillamine may reduce its effectiveness.
The incompatibility of (pharmaceutical) vitamin B6 with B12 and B1 is noted.
The medication in question significantly reduces the anti-parkinsonian activity of the drug Levodopa.
The combination of this agent with hormonal contraceptives can increase the concentration of pyridoxine in the plasma.
The use of Pyridoxine with phenobarbital and phenytoin reduces the concentration of these elements in the blood.
With extreme caution, the medication in question is used for IHD, as well as for ulcers of the digestive tract.
When severe violations of the liver vitamin B6 in high dosages can cause deterioration of its function.
What can replace the drug Pyridoxine? Instructions for use (injections are often replaced by a tablet form of this tool) does not provide an answer to this question. Therefore, in the process of selecting analogues should consult a doctor.
Pyridoxine is a vitamin B6. It is included in the set of combined means, including such as Magne B6, Hepasteril-A, Pernexin Elixir, Essentiale, Hepasteril-B, and Lipostabil. It should also be noted that the analogues of this drug are: Pyridobene, Vitamin B6, Betsilan, Adermin, Pirivitol, Benadon, Bedoksin, Hexabetalin, Hexabibex, Hexabion other.
Feedback on this tool is mostly positive. Experts note that the drug in question is very often prescribed to patients in the course of complex treatment of a wide variety of disorders, including B6 hypovitaminosis, diabetes, leukopenia, atherosclerosis, and so on. In most cases, Pyridoxine significantly improves the therapeutic effect of other medicines, as well as accelerates the process of recovery of the patient.
As for the patients, they are also satisfied with the results of the treatment. Among the many positive messages there are also those that speak of the development of negative effects (for example, an increase in the acidity of the gastric contents, which causes severe pain in people with gastritis).