With various disorders of the intestinal microflora, ranging from dipping and ending with dysbiosis in children, Phthalazole comes to the rescue – a synthetic antimicrobial drug with a broad spectrum of antimicrobial (bacteriostatic) action, especially in relation to the intestinal flora.
The drug has a detrimental effect on bacteria that cause infections in the digestive system. In addition, Phthalazole has an anti-inflammatory effect, and also contributes to the production of glucocorticosteroids – natural hormones that inhibit inflammatory processes in the body.
Immediately it should be noted that Ftalazol belongs to the group of sulfonamides, and not antibiotics. Despite the fact that the mechanism of action of such agents, in principle, is similar (they are embedded in the structure of microorganisms and from the inside interfere with the metabolic processes in their cells), Phtalasol does not belong to antibiotic drugs.
pros This drug product is as follows:
- Negative microflora destroyed by the active substance is removed from the gastrointestinal tract in a natural way along with feces in the process of defecation. With them come the remains of the medicine;
- Only one tenth of the drug taken is absorbed into the body. It penetrates through the blood into the liver and is excreted by the kidneys (with urine);
- Phthalazole does not accumulate in the body, does not cause addiction, and its effectiveness does not decrease even with repeated treatment of diarrhea.
Phthalazole is available in a single dosage form – tablets for oral administration.
The main active ingredient Phthalazole is phthalylsulfathiazole (500 mg).
Sulfathiazole penetrates the cell of the pathogen through the cell wall, inhibits the metabolism of folic acid, which is necessary for most bacteria to synthesize components of nucleic acids, namely, purine and pyrimidine nitrogenous bases, which stops the synthesis of daughter DNA and makes reproduction impossible.
In the tissues, the active substance does not accumulate even with prolonged use of Ftalazol tablets, so there is no addiction or decrease in effectiveness when they are re-used.
This drug is advisable to have in every home medicine chest. It helps quite quickly, stops diarrhea of any origin, which reduces the loss of fluid in the human body and effectively prevent possible dehydration.
Indications for use Ftalazol
According to the instructions for use, Ftalazol can be used for various violations of the functions of the intestine, which have arisen under the influence of a violation of the quantitative composition and diet. That is, after a period of strict diet or out of starvation. Additionally, the drug reduces the effects of high levels of gas (flatulence).
Phthalazole is intended for the treatment of such diseases:
- colitis, enterocolitis, gastroenteritis,
- diarrhea of various origins.
In addition, this drug has a good effect in the case of its use in order to prevent suppurative complications during operations on the intestine.
Phthalazole is indicated for patients without infectious lesions of the intestinal mucosa, in case they are trained for surgery. Also, the tool is prescribed to children in advanced cases of dysbiosis, which is triggered by the use of a wide range of antibacterial drugs. In this case, Phthalazole stops the symptoms of dysbacteriosis.
Instructions for use Ftalazol dosage
Since Ftalazol is from the sulfonamide group, then, like other medicines or its analogs, they are drunk before meals, in half an hour. Doctors recommend to consume during the course of 2-3 liters of free fluid per day.
According to the instructions Ftalazol can not take more than 2 g at a time and more than 7 g per day.
Adults – 1-2 g every 4-6 hours for 5-7 days. Higher doses for adults inside: single – 2 g, daily – 7 g. Children up to 3 years old – 200 mg / kg / day in 3 doses for 7 days. Children older than 3 years – 400-750 mg (depending on age) 4 times / day.
A single dose of Ftalazol use in children aged 3 to 7 years is 0.4 – 0.5 g, and in age from 8 to 14 years – 0.5 – 0.75 g. The course of treatment for children should not exceed 7 days.
In the event of further relapse (re-development of the disease), the course of Ftalazole should be repeated again as follows: 1-2 days: 1 ton. Every 4-5 hours (approximately 5-6 tonnes per day); 3-4 day: 1 t. 3-4 p. per day; 5-6 day: 1 t. 2-3 p. for the day.
The treatment regimen, features of the intake and the exact dosage of Ftalazol depends on the disease, the patient’s chronic pathologies and age.
Simultaneously with Phthalazole, it is advisable to prescribe vitamins of group B, since, due to the inhibition of the growth of Escherichia coli, the synthesis of vitamins of this group decreases.
The drug does not have a negative impact on the psychomotor functions of the human body, and therefore, during therapy with Phthalazole, it is allowed to drive vehicles and work with potentially dangerous mechanisms.
Before you start taking the medicine, you should make sure that there are no symptoms of intoxication and dehydration, expressed in dizziness, weakness, increased body temperature, nausea, and severe vomiting. If one of the above symptoms Ftalazol is contraindicated, it is necessary to urgently seek medical help.
Consumption of alcohol is contraindicated, which in combination with the active compound Phthalazole phthalylsulfathiazole can lead to serious poisoning.
The disease, the nature of its course, the age of the patient, his condition – these are the factors that affect the indications for prescribing pills, the dosage and frequency. But, from whatever the doctor prescribed Ftalazol tablets or its analogue, he should check the sensitivity of the microflora, which provoked the disease.
Side effects and contraindications Phtalazol
- pain in the intestine (lower abdomen);
- increased gassing;
- decrease or complete lack of appetite;
- intestinal candidiasis development;
- difficult act of defecation;
Often there are allergic reactions – rash on the skin, redness of the skin, sneezing, tearing. In this case, you should immediately stop taking the drug and consult a doctor to replace it with a suitable drug.
In case of overdose, Ftalazol most often causes headache or migraine pain, fluctuations in the emotional background, nausea, vomiting, diarrhea, damage to the oral cavity (stomatitis, gingivitis, glossitis), as well as gastritis, cholangitis, cholecystitis and hepatitis; the most frequent symptoms of urolithiasis, sometimes until complete blockage of urination.
In case of overdose, for the purpose of partial rehabilitation, preparations containing folic acid (vitamin B9) are used.
Symptomatic treatment should also be applied.
- Renal failure;
- Infant age up to two years;
- Hypersensitivity to the drug;
- Blood diseases;
- Intestinal obstruction;
- Toxic goiter;
The use of the drug during pregnancy and lactation is possible only in the case when the expected benefit to the mother outweighs the potential risk to the child.
Children under two months of age may take phthalazole only in case of congenital toxoplasmosis.
Analogues Phthalazol List
- Fortecortin Mono;
Important – the instructions for use of Ftalazol, price and reviews to analogues do not apply and can not be used as a guide for the use of drugs of similar composition or action. All therapeutic appointments should be done by a doctor. When replacing Ftalazol with an analog, it is important to get expert advice, you may need to change the course of therapy, dosages, etc. Do not self-medicate!
Ten years ago, this drug was the only one against diarrhea. But today there are several of its analogues, although some continue to prefer Ftalazol. Maybe because of its reasonable price, because all modern drugs today are expensive and not everyone can buy them.
Reviews of doctors on the use of Ftalazol are good – the medicine quickly copes with diarrhea, it is inexpensive and effective. The use of the described means requires an individual approach and medical supervision. Do not risk your health, take Ftalazol tablets (from which they help, you are now well known) only by strict indications!