Actovegin is a broad-spectrum drug aimed at the regeneration of various tissues of the human body. The drug accelerates and stimulates the metabolism in the cells, increasing their life potential. The instructions attached to the drug contain all the information about the properties, advantages and disadvantages of the drug.
Brief instructions for use Actovegin
Actovegin – a drug to improve the metabolic and regenerating mechanism within cells. It stimulates the energy processes and the functionality of the metabolism in the human body, helps recovery at the intracellular level and tissue healing.
Additionally, the drug enhances blood circulation. Actovegin activates and stimulates the processes of renewal, improves cell nutrition. All this produces the resistance of tissues of various organs to hypoxia – oxygen starvation.
Actovegin is a preparation based on the liberated protein from calves’ blood extract, obtained by dialysis and filtration.
The active ingredient of the drug is the deproteinized hemoderivate of the blood of young calves. Developed and patented Actovegin Austrian company Nycomed.
Available in various forms:
- Cream for external use 5%;
- Ointment for external use of 5%;
- Gel outer 5%;
- Ophthalmic gel 20%;
- Dragee with the amount of active substance 500 milligrams;
- Solution for injection with different doses – 400 milligrams, 200 milligrams, 80 milligrams of the active substance;
- Solution for infusion with glucose and sodium chloride;
- Tablets in a soluble shell with a volume of active substance 200 milligrams.
The main drug manufacturers are well-known pharmaceutical companies:
- KRKA, Slovenia;
- Nicomed, Austria;
- Sotex-Farmfirm, Austria;
- Hafslund, Austria;
- Unic Pharmaceuticals, India;
- Nycomed, Germany;
- Sotex FarmFirma, Russia.
In what cases is the drug used?
Indications for use of the drug are various conditions and diseases:
- Insufficient blood supply and blood circulation of the brain;
- Low level of oxygen in the blood;
- Ischemic stroke;
- Head and brain injuries;
- Decrease of vascular tone with violation of their functionality;
- Deviations in the nutrition of skin cells;
- Violation of the functionality of the valve apparatus;
- Ulcers of varying degrees and etiology;
- Treatment and prevention of radiation sickness;
- Corneal lesions of various etiologies;
- Damage to the sclera;
- Inflammation of the cornea;
- Eye ulcers;
- Implications of corneal transplantation;
- Prevention of corneal abrasions, as a result of improper selection and wearing of lenses;
- Diabetic polyneuropathy;
- Placental insufficiency;
- Prevention of preterm birth;
- Transferred myocardial infarction;
- Cerebrovascular disease and its consequences;
- Radiation cystitis;
- Open wounds;
- Posttraumatic infection.
All pharmakinetic based on the action of the physiological components of the drug.
Features of use of Actovegin and contraindications
Depending on the dosage form of Actovegin and the disease, as a result of which the medicine is prescribed, the doctor prescribes an individual method of administration. The drug can be used in three ways: orally, parenterally, externally (topically).
According to the attached instructions:
- Drops and pills three times a day for 1-2 pieces;
- Intravenously and intraarterially (depending on the severity of the disease and individual characteristics) initially 10-20 milliliters. Subsequently prescribed 5 milliliters daily.
- Drip in the form of infusions once a day for 250 milliliters of the drug solution with a speed of up to 3 milliliters in 1 minute. The course is not more than 20 days. It is forbidden to add to the solution Actovegin other drugs.
Parenteral administration of the drug requires caution and control. This is due to the possible development of allergic anaphylactic shock. At the same time, it is necessary to additionally monitor the patient’s blood pressure level and the indicators of water and electrolyte metabolism.
- The gel is used as prescribed by the physician to cleanse and heal superficial wounds and ulcers. Sometimes used for drawing in the form of dressings and compresses. Change the bandages at least once a week. For wet surfaces – several times a day.
- The cream is used to treat wounds of different etiologies and improve their healing.
- Ointment Actovegin used in the treatment of non-healing skin lesions. Recommended for the prevention of bedsores.
- Eye Gel prescribes an ophthalmologist for the treatment of eye diseases. Usually used 1 drop of gel three times a day.
Opened packaging can be stored after opening no more than 30 days. In the case of particles in the solution or the appearance of opacity, the use of the drug is prohibited. Side effects may occur due to increased sensitivity to the active substance of the drug.
In rare cases, allergic reactions may occur:
- Drug fever;
- Increased body temperature;
- Pain in the heart;
- The occurrence of tides;
- Hyperemia of the skin;
- Itching, burning and irritation in the area of local application.
Development is rarely possible:
- Hypo or hypertension;
- Disruption of the work of certain organs;
- Frequent heavy breathing;
- Sore throat;
- Muscle spasms and pains;
- Loss of consciousness.
In cases of overdose and self-use of the drug can be observed:
- Stomach cramps;
- Abdominal pain;
- Nausea, passing into vomiting;
Therefore, it is extremely important to take and use the drug under the supervision of a doctor and only for its intended purpose.
There are some contraindications for the use of medication in treatment. For the drug Actovegin contraindications are as follows:
- Child age up to 3 years;
- Hypersensitivity to Actovegin and its analogues;
- Heart failure with decompensation;
- Pulmonary edema;
- Diabetes mellitus (when using glucose diffusion).
With all this, the drug is recommended for use during pregnancy for the prevention of phenoplacental insufficiency. However, if side effects are observed, the use of the medication is immediately terminated.
Unreasonable use of Actovegin is prohibited, as with improper treatment with violation of the conditions of use, critical states are possible. Instructions for the drug is exploratory in nature, not being a guide to action.
How is vegetative dystonia treated?
Many people are faced with a diagnosis such as vegetative-vascular dystonia, a disease based on an imbalance in the work of the autonomic nervous system. The disease is not life threatening, but can often be a precursor to other serious diseases.
If this is confirmed with the help of a diagnostic examination, then treatment of the AVR with medications is required. Drug treatment is prescribed by the doctor, conducting the necessary diagnostic studies, comparing the patient’s complaints and test results.
Often in the treatment of VSD requires the use of Actovegin, which interferes with energy cellular processes that affect the state of mental energy. This is a great antioxidant that positively affects cell regeneration, blood supply and blood circulation in the brain and other organs. Actovegin has a medicinal effect on the body with the IRR in the form of improved metabolism of brain cells.
IRR is a disease that is often caused by the fear of death. Antidepressants, sedatives, antipsychotics and antioxidants, in particular, Actovegin, together with complex treatment help to get rid of this disease.
Coping with chronic stress, fatigue, restoring balance in the body, patients recover from the IRR quickly. Additional measures in a favorable outcome of treatment are often compliance with the diet and the day, exercise, optimistic perception of your life, setting goals, overcoming phobias, hardening the body, proper nutrition.
Learn about the treatment of VSD from the proposed video.
Actovegin is a universal medicine that, when applied correctly under the supervision of a physician, can help even with the “hopeless” case itself, by improving the general condition of the patient.