In this article, you can read the instructions for use of the drug. Erespal. Presented reviews of visitors to the site – the consumers of this medicine, as well as the opinions of doctors of specialists on the use of Erespal in their practice. A big request to add your feedback on the drug more actively: the medicine helped or did not help to get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogs of Erespal with available structural analogues. Use for the treatment of cough, hoarseness, sore throat and other infections of the upper and lower respiratory tract in adults, children, as well as during pregnancy and breastfeeding.
Erespal – anti-inflammatory and anti-bronchoconstrictor activity of the drug Erespal is due to the fact that fenspiride reduces the production of a number of biologically active substances (cytokines, especially tumor necrosis factor alpha (TNF-alpha), arachidonic acid derivatives, free radicals) that play an important role in the development of inflammation and bronchospasm.
Inhibition of arachidonic acid metabolism by fenspiride is potentiated by the blockade of histamine H1 receptors,
Fenspirid also has a spasmolytic effect.
The composition of the drug
1 tablet, coated, contains fenspirid hydrochloride 80 mg. Excipients: disubstituted calcium phosphate, hypromellose, povidone, colloidal anhydrous silicon, magnesium stearate, titanium dioxide, glycerol, macrogol 6000; in a blister of 15 pcs., in a box of 2 blisters.
1 ml of syrup – 2 mg of fenspiride hydrochloride. Auxiliary substances: honey aroma (honey, rum, alcoholate and alcoholic extracts of honey, rose and orange flowers), licorice root extract (concentrated tincture of licorice root, glucose syrup, anise oil) and vanilla extract (water-alcohol decoction of vanilla pods, glycerin, dye sunset yellow S, methyl parahydroxybenzoate, propyl parahydroxybenzoate, saccharin, sucrose, potassium sorbate, distilled water); in a bottle of 150 ml, in a box 1 bottle.
Well absorbed from the digestive tract. Excreted mainly in the urine (90%), through the intestine 10%.
Diseases of the upper and lower respiratory tract:
- rhinopharyngitis and laryngitis;
- bronchitis (with or without chronic respiratory failure);
- bronchial asthma (as part of complex therapy);
- respiratory symptoms (cough, hoarseness, sore throat) for measles, whooping cough, flu;
- infectious diseases of the respiratory tract, accompanied by cough, when shown standard antibiotic therapy;
- otitis media and sinusitis of various etiologies.
Forms of release
Tablets, film coated 80 mg.
Syrup 2 mg / ml (child form of the drug).
Instructions for use and dosage
Adults are prescribed 80 mg (1 tablet) 2-3 times a day or 3-6 tablespoons (45-90 ml) of syrup per day. 1 tablespoon contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.
The maximum daily dose is 240 mg. The duration of treatment is determined by the doctor.
Erespal in the form of tablets is not intended to treat children and adolescents under the age of 18 years. For use of the drug in this category of patients recommended Erespal in the form of syrup.
Children and adolescents are prescribed at the rate of 4 mg / kg of body weight per day. Children aged 0 to 2 years (body weight up to 10 kg) – 2-4 teaspoons of syrup (10-20 ml) per day, can be added to the bottle with nutrition (1 tsp contains 10 mg of fenspirid hydrochloride and 3 gsaharozy). Children aged 2 to 16 years (body weight more than 10 kg) – 2-4 tablespoons of syrup (30-60 ml) per day.
The drug should be taken before meals. Shake syrup before use.
- moderate tachycardia, the severity of which decreases with a decrease in the dose of the drug
- gastrointestinal disorders
- epigastric pain
- erythema, rash, urticaria, angioedema.
- children’s age up to 18 years (for tablets);
- Hypersensitivity to the active substance and / or any of the components of the drug.
Use during pregnancy and lactation
Taking the drug during pregnancy is not recommended.
Fenspiride therapy is not a reason to terminate the onset of pregnancy.
Do not use Erespal during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.
For the treatment of children and adolescents under 18 years old, you should use Erespal syrup.
The preparation contains the dye Sunset yellow S, as a result of which Erespal’s administration can provoke the development of allergic reactions, including asthma attacks, especially in people with hypersensitivity to aspirin.
Due to the possible sedative effect when taking histamine H1 receptor blockers, Erespal is not recommended in combination with drugs that have a sedative effect, or together with alcohol.
Analogs drug Erespal
Structural analogues of the active substance: