Sometimes it happens that the spouses passionately dream of having children, and doctors say that all tests are good, and both future parents are healthy, and pregnancy is not happening. What is the reason? Let’s try to figure it out. It turns out that the case may be not only in the health status of the husband and wife separately, the success of conception depends largely on their immunological compatibility. In some cases, the woman’s body perceives sperm as harmful agents that threaten health, antigens, and begins to actively develop antibody proteins against spermatozoa, “neutralizing” them and thereby suppressing their ability to fertilize. It is then that pregnancy does not occur, because the sperm can not meet with the egg. To find out if the couple has such a problem, a compatibility test or a postcoital test is assigned to the husband and wife.
One of the simplest methods for diagnosing this pathology is the analysis of the compatibility of spouses. For the implementation of this test, a sample of cervical mucus is taken from the cervical canal of a woman within 6-12 hours after intercourse. Cervical mucus is examined under a conventional microscope in order to determine the total number of spermatozoa contained in it and their mobility. If there are a lot of spermatozoa and they are actively moving, the spouses are immunologically compatible. If in the cervical mucus there are no sperm cells at all or there are single and immobile ones, it means that there is a problem of incompatibility of the spouses. In order to obtain reliable results, the compatibility analysis is carried out on the day of ovulation, as a rule, on days 14-16, since in the period before and after ovulation, cervical mucus normally suppresses the activity of male germ cells.
If you decide on the procedure
With the mutual consent of both spouses to analyze the compatibility, you need to prepare for the fact that such analyzes will be carried out a few – to obtain reliable results. Before analyzing compatibility, it is advisable to measure the basal temperature for 3 months and record this data. In this case, the doctors of the “Euromedprestige” clinic will help the expectant mother to accurately determine the time of ovulation and, therefore, the date of the test. You can track the timing of ovulation and with the help of ultrasound. If an incompatibility is found in the result of the test, cross-sectional studies are carried out: the partner’s cervical mucus and the donor’s sperm, and vice versa, the partner’s sperm and the donor’s cervical mucus. This clarifies whether the woman’s immune response is the cause of the incompatibility, or whether the problem lies in the sperm. In such situations, doctors recommend additional blood tests to be carried out to determine the presence of antibodies to the husband’s sperm and their concentration. Also, the spouses need an analysis of the compatibility of the Rh factor to determine whether Rh-conflict, the woman’s immune response to the fetus, can develop during pregnancy. If the woman’s rhesus is negative, then she needs to enter